Distinct place cell dynamics in CA1 and CA3 encode experience in new environments
To understand how spatial representations emerge and evolve across hippocampal subfields, we compared trial-to-trial dynamics of place cells in CA1 and CA3 in new environments and across days. CA1 place fields form early, shift backwards and partially remap across days whereas in CA3 they develop gr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-23260-3 |
| _version_ | 1818840654851080192 |
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| author | Can Dong Antoine D. Madar Mark E. J. Sheffield |
| author_facet | Can Dong Antoine D. Madar Mark E. J. Sheffield |
| author_sort | Can Dong |
| collection | DOAJ |
| description | To understand how spatial representations emerge and evolve across hippocampal subfields, we compared trial-to-trial dynamics of place cells in CA1 and CA3 in new environments and across days. CA1 place fields form early, shift backwards and partially remap across days whereas in CA3 they develop gradually and are more stable, suggesting distinct functional roles in representing space. |
| first_indexed | 2024-12-19T04:13:38Z |
| format | Article |
| id | doaj.art-e47b3aace2934aa888552fcb6ae7820d |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-19T04:13:38Z |
| publishDate | 2021-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e47b3aace2934aa888552fcb6ae7820d2022-12-21T20:36:21ZengNature PortfolioNature Communications2041-17232021-05-0112111310.1038/s41467-021-23260-3Distinct place cell dynamics in CA1 and CA3 encode experience in new environmentsCan Dong0Antoine D. Madar1Mark E. J. Sheffield2Department of Neurobiology and Institute for Neuroscience, University of ChicagoDepartment of Neurobiology and Institute for Neuroscience, University of ChicagoDepartment of Neurobiology and Institute for Neuroscience, University of ChicagoTo understand how spatial representations emerge and evolve across hippocampal subfields, we compared trial-to-trial dynamics of place cells in CA1 and CA3 in new environments and across days. CA1 place fields form early, shift backwards and partially remap across days whereas in CA3 they develop gradually and are more stable, suggesting distinct functional roles in representing space.https://doi.org/10.1038/s41467-021-23260-3 |
| spellingShingle | Can Dong Antoine D. Madar Mark E. J. Sheffield Distinct place cell dynamics in CA1 and CA3 encode experience in new environments Nature Communications |
| title | Distinct place cell dynamics in CA1 and CA3 encode experience in new environments |
| title_full | Distinct place cell dynamics in CA1 and CA3 encode experience in new environments |
| title_fullStr | Distinct place cell dynamics in CA1 and CA3 encode experience in new environments |
| title_full_unstemmed | Distinct place cell dynamics in CA1 and CA3 encode experience in new environments |
| title_short | Distinct place cell dynamics in CA1 and CA3 encode experience in new environments |
| title_sort | distinct place cell dynamics in ca1 and ca3 encode experience in new environments |
| url | https://doi.org/10.1038/s41467-021-23260-3 |
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