Extracellular Vesicles Derived from MDA-MB-231 Cells Trigger Neutrophils to a Pro-Tumor Profile

Extracellular Vesicles Derived from MDA-MB-231 Cells Trigger Neutrophils to a Pro-Tumor Profile

Immune system cells, including neutrophils, are recruited by the tumor microenvironment as a site of chronic inflammation and begin to favor tumor growth. Neutrophils present in the tumor site are called tumor-associated neutrophils (TAN) and can present two phenotypes: N1 (antitumor) or N2 (pro-tum...

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Bibliographic Details
Main Authors: Carolinne Amorim, Clara Luisa Docasar, Daniel Guimarães-Bastos, Ana Clara Frony, Christina Barja-Fidalgo, Mariana Renovato-Martins, João Alfredo Moraes
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
extracellular vesicles
breast cancer
inflammation
tumor-associated neutrophils
Online Access:https://www.mdpi.com/2073-4409/11/12/1875

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