Second Trimester Fetal Loss Due to <i>Citrobacter koseri</i> Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM)
<i>Citrobacter koseri</i> is a facultative anaerobic, motile, non-spore-forming Gram-negative bacillus, which belongs to the family of Enterobacteriaceae. Severe infections due to <i>Citrobacter</i> spp. have been reported in the urinary tract, respiratory airways, intra-abdo...
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MDPI AG
2022-01-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/1/159 |
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| author | Maria Paola Bonasoni Giuseppina Comitini Mariangela Pati Giuseppe Russello Loredana Vizzini Marcellino Bardaro Pietro Pini Roberta Marrollo Andrea Palicelli Giulia Dalla Dea Edoardo Carretto |
| author_facet | Maria Paola Bonasoni Giuseppina Comitini Mariangela Pati Giuseppe Russello Loredana Vizzini Marcellino Bardaro Pietro Pini Roberta Marrollo Andrea Palicelli Giulia Dalla Dea Edoardo Carretto |
| author_sort | Maria Paola Bonasoni |
| collection | DOAJ |
| description | <i>Citrobacter koseri</i> is a facultative anaerobic, motile, non-spore-forming Gram-negative bacillus, which belongs to the family of Enterobacteriaceae. Severe infections due to <i>Citrobacter</i> spp. have been reported in the urinary tract, respiratory airways, intra-abdominal organs, skin and soft tissue, eye, bone, bloodstream, and central nervous system. In newborns, <i>C. koseri</i> is a well-known cause of meningitis, cerebral abscesses, brain adhesions, encephalitis, and pneumocephalus. Infection can be acquired through vertical maternal transmission or horizontal hospital settings; however, in many cases, the source is unknown. Preterm premature rupture of membranes (PPROM), caused by <i>C. koseri</i>, has rarely been described. Herein, we describe a case of PPROM at 16 weeks and 3 days of gestation, leading to anhydramnios. The parents opted for legal termination of the pregnancy, as the prognosis was very poor. <i>C. koseri</i> was isolated postmortem from a placental subamniotic swab and parenchymal sample, as well as fetal blood and lung. To the best of our knowledge, this is the first case of early second-trimester PPROM in which <i>C. koseri</i> infection was demonstrated. |
| first_indexed | 2024-03-10T01:38:54Z |
| format | Article |
| id | doaj.art-e47c102a274f4aad844d87033aa9f217 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T01:38:54Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-e47c102a274f4aad844d87033aa9f2172023-11-23T13:29:17ZengMDPI AGDiagnostics2075-44182022-01-0112115910.3390/diagnostics12010159Second Trimester Fetal Loss Due to <i>Citrobacter koseri</i> Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM)Maria Paola Bonasoni0Giuseppina Comitini1Mariangela Pati2Giuseppe Russello3Loredana Vizzini4Marcellino Bardaro5Pietro Pini6Roberta Marrollo7Andrea Palicelli8Giulia Dalla Dea9Edoardo Carretto10Pathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyDepartment of Obstetrics & Gynaecology, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyDepartment of Obstetrics & Gynaecology, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyClinical Microbiology Laboratory, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyClinical Microbiology Laboratory, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyClinical Microbiology Laboratory, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyClinical Microbiology Laboratory, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyClinical Microbiology Laboratory, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyPathology Unit, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, ItalyPathology Unit, “Maggiore della Carità” Hospital, 28100 Novara, ItalyClinical Microbiology Laboratory, Azienda USL-IRCCS di Reggio Emilia, 42123 Reggio Emilia, Italy<i>Citrobacter koseri</i> is a facultative anaerobic, motile, non-spore-forming Gram-negative bacillus, which belongs to the family of Enterobacteriaceae. Severe infections due to <i>Citrobacter</i> spp. have been reported in the urinary tract, respiratory airways, intra-abdominal organs, skin and soft tissue, eye, bone, bloodstream, and central nervous system. In newborns, <i>C. koseri</i> is a well-known cause of meningitis, cerebral abscesses, brain adhesions, encephalitis, and pneumocephalus. Infection can be acquired through vertical maternal transmission or horizontal hospital settings; however, in many cases, the source is unknown. Preterm premature rupture of membranes (PPROM), caused by <i>C. koseri</i>, has rarely been described. Herein, we describe a case of PPROM at 16 weeks and 3 days of gestation, leading to anhydramnios. The parents opted for legal termination of the pregnancy, as the prognosis was very poor. <i>C. koseri</i> was isolated postmortem from a placental subamniotic swab and parenchymal sample, as well as fetal blood and lung. To the best of our knowledge, this is the first case of early second-trimester PPROM in which <i>C. koseri</i> infection was demonstrated.https://www.mdpi.com/2075-4418/12/1/159<i>Citrobacter koseri</i>preterm premature rupture of membraneschorioamnionitisvertical transmission |
| spellingShingle | Maria Paola Bonasoni Giuseppina Comitini Mariangela Pati Giuseppe Russello Loredana Vizzini Marcellino Bardaro Pietro Pini Roberta Marrollo Andrea Palicelli Giulia Dalla Dea Edoardo Carretto Second Trimester Fetal Loss Due to <i>Citrobacter koseri</i> Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM) Diagnostics <i>Citrobacter koseri</i> preterm premature rupture of membranes chorioamnionitis vertical transmission |
| title | Second Trimester Fetal Loss Due to <i>Citrobacter koseri</i> Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM) |
| title_full | Second Trimester Fetal Loss Due to <i>Citrobacter koseri</i> Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM) |
| title_fullStr | Second Trimester Fetal Loss Due to <i>Citrobacter koseri</i> Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM) |
| title_full_unstemmed | Second Trimester Fetal Loss Due to <i>Citrobacter koseri</i> Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM) |
| title_short | Second Trimester Fetal Loss Due to <i>Citrobacter koseri</i> Infection: A Rare Cause of Preterm Premature Rupture of Membranes (PPROM) |
| title_sort | second trimester fetal loss due to i citrobacter koseri i infection a rare cause of preterm premature rupture of membranes pprom |
| topic | <i>Citrobacter koseri</i> preterm premature rupture of membranes chorioamnionitis vertical transmission |
| url | https://www.mdpi.com/2075-4418/12/1/159 |
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