Two Functionally Distinct Sources of Actin Monomers Supply the Leading Edge of Lamellipodia

Two Functionally Distinct Sources of Actin Monomers Supply the Leading Edge of Lamellipodia

Lamellipodia, the sheet-like protrusions of motile cells, consist of networks of actin filaments (F-actin) regulated by the ordered assembly from and disassembly into actin monomers (G-actin). Traditionally, G-actin is thought to exist as a homogeneous pool. Here, we show that there are two function...

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Bibliographic Details
Main Authors:	Eric A. Vitriol, Laura M. McMillen, Maryna Kapustina, Shawn M. Gomez, Dimitrios Vavylonis, James Q. Zheng
Format:	Article
Language:	English
Published:	Elsevier 2015-04-01
Series:	Cell Reports
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124715003022

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