| Summary: | Agriculture plays a crucial role in sustaining the global population with food safety and security. The inadequacy of current agrochemicals in effectively controlling microbial infestations necessitates immediate attention. The over usage of agrochemicals has posed significant threat to agriculture by hampering the crop productivity, increased disease outbreaks and spread resistant microorganisms. This review addresses the pressing issue of drug-resistant microbial pathogens and their detrimental impact on the agricultural system. The use of nanoagrosomes has gained significant attention as a potential solution for combating drug-resistant pathogens due to their unique physicochemical properties, which can be tailored to target specific activities. A diverse of nanoagrosomes is widely practiced to attenuate specific roles which has been outline in the review. It also shed light on their effectiveness in combating drug-resistant pathogens and their role in promoting agricultural sustainability by expanding scientific understanding of nanoagrosomes as a future prospect for management of drug resistance.
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