Mechanisms of Development and Variants of Therapeutic Management of Steroid Resistance in Patients with Atopic Dermatitis
Skin is the natural habitat for complex bacterial, fungal, and viral communities (ecosystems). The microbiome of such communities is always in close relationship with the host genome, and the development of these ecosystems happens under the effects of morpho-physiological and immunological characte...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2021-11-01
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| Series: | Вопросы современной педиатрии |
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| Online Access: | https://vsp.spr-journal.ru/jour/article/view/2754 |
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| author | Nikolay N. Murashkin Roman V. Epishev Alexander I. Materikin Eduard T. Ambarchyan Leonid A. Opryatin Roman A. Ivanov |
| author_facet | Nikolay N. Murashkin Roman V. Epishev Alexander I. Materikin Eduard T. Ambarchyan Leonid A. Opryatin Roman A. Ivanov |
| author_sort | Nikolay N. Murashkin |
| collection | DOAJ |
| description | Skin is the natural habitat for complex bacterial, fungal, and viral communities (ecosystems). The microbiome of such communities is always in close relationship with the host genome, and the development of these ecosystems happens under the effects of morpho-physiological and immunological characteristics of the skin (sebaceous glands concentration, humidity, and temperature) and environmental factors. Metagenomic studies have shown significant diversity in skin ecosystems. Moreover, the role of commensal microorganisms in skin immune response modulating to various agents and, thus, its correlation with skin diseases pathogenesis is no longer in doubt. New probiotic and antimicrobial agents for external treatment have been developed according to these knowledges. |
| first_indexed | 2024-03-12T04:48:23Z |
| format | Article |
| id | doaj.art-e4816c2c4e1642859cca17ef76c69095 |
| institution | Directory Open Access Journal |
| issn | 1682-5527 1682-5535 |
| language | English |
| last_indexed | 2025-03-14T09:37:23Z |
| publishDate | 2021-11-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj.art-e4816c2c4e1642859cca17ef76c690952025-03-02T11:34:24Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352021-11-0120537037510.15690/vsp.v20i5.23091984Mechanisms of Development and Variants of Therapeutic Management of Steroid Resistance in Patients with Atopic DermatitisNikolay N. Murashkin0Roman V. Epishev1Alexander I. Materikin2Eduard T. Ambarchyan3Leonid A. Opryatin4Roman A. Ivanov5National Medical Research Center of Children's Health; Sechenov First Moscow State Medical University (Sechenov University); Central State Medical AcademyNational Medical Research Center of Children's HealthNational Medical Research Center of Children's HealthResearch Institute of Pediatrics and Children's Health in “Central Clinical Hospital of the Russian Academy of Sciences”National Medical Research Center of Children's HealthNational Medical Research Center of Children's HealthSkin is the natural habitat for complex bacterial, fungal, and viral communities (ecosystems). The microbiome of such communities is always in close relationship with the host genome, and the development of these ecosystems happens under the effects of morpho-physiological and immunological characteristics of the skin (sebaceous glands concentration, humidity, and temperature) and environmental factors. Metagenomic studies have shown significant diversity in skin ecosystems. Moreover, the role of commensal microorganisms in skin immune response modulating to various agents and, thus, its correlation with skin diseases pathogenesis is no longer in doubt. New probiotic and antimicrobial agents for external treatment have been developed according to these knowledges.https://vsp.spr-journal.ru/jour/article/view/2754atopic dermatitismicrobiomestaphylococcus aureuschildrensteroid resistance |
| spellingShingle | Nikolay N. Murashkin Roman V. Epishev Alexander I. Materikin Eduard T. Ambarchyan Leonid A. Opryatin Roman A. Ivanov Mechanisms of Development and Variants of Therapeutic Management of Steroid Resistance in Patients with Atopic Dermatitis Вопросы современной педиатрии atopic dermatitis microbiome staphylococcus aureus children steroid resistance |
| title | Mechanisms of Development and Variants of Therapeutic Management of Steroid Resistance in Patients with Atopic Dermatitis |
| title_full | Mechanisms of Development and Variants of Therapeutic Management of Steroid Resistance in Patients with Atopic Dermatitis |
| title_fullStr | Mechanisms of Development and Variants of Therapeutic Management of Steroid Resistance in Patients with Atopic Dermatitis |
| title_full_unstemmed | Mechanisms of Development and Variants of Therapeutic Management of Steroid Resistance in Patients with Atopic Dermatitis |
| title_short | Mechanisms of Development and Variants of Therapeutic Management of Steroid Resistance in Patients with Atopic Dermatitis |
| title_sort | mechanisms of development and variants of therapeutic management of steroid resistance in patients with atopic dermatitis |
| topic | atopic dermatitis microbiome staphylococcus aureus children steroid resistance |
| url | https://vsp.spr-journal.ru/jour/article/view/2754 |
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