A Novel Conserved Linear Neutralizing Epitope on the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein

A Novel Conserved Linear Neutralizing Epitope on the Receptor-Binding Domain of the SARS-CoV-2 Spike Protein

ABSTRACT The continuous emergence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has made it challenging to develop broad-spectrum prophylactic vaccines and therapeutic antibodies. Here, we have identified a broad-spectrum neutralizing antibody and its highly conserv...

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Bibliographic Details
Main Authors: Rong-Hong Hua, Shu-Jian Zhang, Bei Niu, Jin-Ying Ge, Ting Lan, Zhi-Gao Bu
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
spike protein
receptor-binding domain
neutralizing antibody
epitope
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01190-23

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