5-Aminosalicylic Acid-induced Myocarditis in a Patient with Atypical Ulcerative Colitis
5-aminosalicylic acid (5-ASA) is used widely to treat ulcerative colitis. The common side effects of 5-ASA include nausea, vomiting, abdominal pain, headache, and skin rash. 5-ASA-induced myocarditis is a rare side effect, and few cases have been reported. 5-ASA-induced myocarditis usually occurs...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Jin Publishing & Printing Co.
2022-01-01
|
| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=5785&vmd=Full |
| Summary: | 5-aminosalicylic acid (5-ASA) is used widely to treat ulcerative colitis. The common side effects of 5-ASA include nausea, vomiting,
abdominal pain, headache, and skin rash. 5-ASA-induced myocarditis is a rare side effect, and few cases have been reported. 5-ASA-induced
myocarditis usually occurs within 2-4 weeks of drug use and causes chest pain and dyspnea. This paper reports 5-ASA-induced
myocarditis in a 31-year-old male patient who took 5-ASA for 20 days prior. The patient was hospitalized with dyspnea that worsened
when lying down, with chest pain radiating to the left neck, fever, and vomiting. Myocarditis was suspected. The work-up included
electrocardiogram, transthoracic echocardiogram, cardiac MRI, and laboratory investigations. The patient’s signs and symptoms improved
within a few days after withdrawing 5-ASA. This case shows that an evaluation including the possibility of myocarditis should
be performed when patients with ulcerative colitis receiving 5-ASA present with cardiac problems, such as dyspnea and chest pain. |
|---|---|
| ISSN: | 1598-9992 2233-6869 |