Impairment of Procedural Learning and Motor Intracortical Inhibition in Neurofibromatosis Type 1 Patients

Background: Cognitive difficulties are the most common neurological complications in neurofibromatosis type 1 (NF1) patients. Recent animal models proposed increased GABA-mediated inhibition as one underlying mechanism directly affecting the induction of long-term potentiation (LTP) and learning. In...

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Bibliographic Details
Main Authors: Máximo Zimerman, Maximilian J. Wessel, Jan E. Timmermann, Sofia Granström, Christian Gerloff, Victor F. Mautner, Friedhelm C. Hummel
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415301183