Polymorphisms of HOMER1 gene are associated with piglet splay leg syndrome and one significant SNP can affect its intronic promoter activity in vitro

Polymorphisms of HOMER1 gene are associated with piglet splay leg syndrome and one significant SNP can affect its intronic promoter activity in vitro

Abstract Background In our previous genome-wide association study (GWAS) on the piglet splay leg (PSL) syndrome, the homer scaffolding protein 1 (HOMER1) was detected as a candidate gene. The aim of this work was to further verify the candidate gene by sequencing the gene and find the significantly...

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Bibliographic Details
Main Authors: Sutong Xu, Xingjie Hao, Min Zhang, Kai Wang, Shuaifeng Li, Xing Chen, Liaohan Yang, Lin Hu, Shujun Zhang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Genetics
Subjects:
HOMER1
Piglet splay leg
Intronic promoter
SNP
Online Access:http://link.springer.com/article/10.1186/s12863-018-0701-0

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