Lifelong single-cell profiling of cranial neural crest diversification in zebrafish

Cranial neural crest generates a wide diversity of cell types. Here the authors perform single-cell profiling of neural crest to identify key enhancers and transcription factors for cell fate competency, thus revealing progressive acquisition of fate potential.

Bibliographic Details
Main Authors: Peter Fabian, Kuo-Chang Tseng, Mathi Thiruppathy, Claire Arata, Hung-Jhen Chen, Joanna Smeeton, Nellie Nelson, J. Gage Crump
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-27594-w
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author Peter Fabian
Kuo-Chang Tseng
Mathi Thiruppathy
Claire Arata
Hung-Jhen Chen
Joanna Smeeton
Nellie Nelson
J. Gage Crump
author_facet Peter Fabian
Kuo-Chang Tseng
Mathi Thiruppathy
Claire Arata
Hung-Jhen Chen
Joanna Smeeton
Nellie Nelson
J. Gage Crump
author_sort Peter Fabian
collection DOAJ
description Cranial neural crest generates a wide diversity of cell types. Here the authors perform single-cell profiling of neural crest to identify key enhancers and transcription factors for cell fate competency, thus revealing progressive acquisition of fate potential.
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spelling doaj.art-e49d20e6f0a74846bc382987b4e1b2292022-12-21T21:19:49ZengNature PortfolioNature Communications2041-17232022-01-0113111310.1038/s41467-021-27594-wLifelong single-cell profiling of cranial neural crest diversification in zebrafishPeter Fabian0Kuo-Chang Tseng1Mathi Thiruppathy2Claire Arata3Hung-Jhen Chen4Joanna Smeeton5Nellie Nelson6J. Gage Crump7Eli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineCranial neural crest generates a wide diversity of cell types. Here the authors perform single-cell profiling of neural crest to identify key enhancers and transcription factors for cell fate competency, thus revealing progressive acquisition of fate potential.https://doi.org/10.1038/s41467-021-27594-w
spellingShingle Peter Fabian
Kuo-Chang Tseng
Mathi Thiruppathy
Claire Arata
Hung-Jhen Chen
Joanna Smeeton
Nellie Nelson
J. Gage Crump
Lifelong single-cell profiling of cranial neural crest diversification in zebrafish
Nature Communications
title Lifelong single-cell profiling of cranial neural crest diversification in zebrafish
title_full Lifelong single-cell profiling of cranial neural crest diversification in zebrafish
title_fullStr Lifelong single-cell profiling of cranial neural crest diversification in zebrafish
title_full_unstemmed Lifelong single-cell profiling of cranial neural crest diversification in zebrafish
title_short Lifelong single-cell profiling of cranial neural crest diversification in zebrafish
title_sort lifelong single cell profiling of cranial neural crest diversification in zebrafish
url https://doi.org/10.1038/s41467-021-27594-w
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