Lifelong single-cell profiling of cranial neural crest diversification in zebrafish
Cranial neural crest generates a wide diversity of cell types. Here the authors perform single-cell profiling of neural crest to identify key enhancers and transcription factors for cell fate competency, thus revealing progressive acquisition of fate potential.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-01-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-27594-w |
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author | Peter Fabian Kuo-Chang Tseng Mathi Thiruppathy Claire Arata Hung-Jhen Chen Joanna Smeeton Nellie Nelson J. Gage Crump |
author_facet | Peter Fabian Kuo-Chang Tseng Mathi Thiruppathy Claire Arata Hung-Jhen Chen Joanna Smeeton Nellie Nelson J. Gage Crump |
author_sort | Peter Fabian |
collection | DOAJ |
description | Cranial neural crest generates a wide diversity of cell types. Here the authors perform single-cell profiling of neural crest to identify key enhancers and transcription factors for cell fate competency, thus revealing progressive acquisition of fate potential. |
first_indexed | 2024-12-18T05:14:38Z |
format | Article |
id | doaj.art-e49d20e6f0a74846bc382987b4e1b229 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-12-18T05:14:38Z |
publishDate | 2022-01-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-e49d20e6f0a74846bc382987b4e1b2292022-12-21T21:19:49ZengNature PortfolioNature Communications2041-17232022-01-0113111310.1038/s41467-021-27594-wLifelong single-cell profiling of cranial neural crest diversification in zebrafishPeter Fabian0Kuo-Chang Tseng1Mathi Thiruppathy2Claire Arata3Hung-Jhen Chen4Joanna Smeeton5Nellie Nelson6J. Gage Crump7Eli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineEli and Edythe Broad California Institute for Regenerative Medicine Center for Regenerative Medicine and Stem Cell Research, Department of Stem Cell Biology and Regenerative Medicine, University of Southern California Keck School of MedicineCranial neural crest generates a wide diversity of cell types. Here the authors perform single-cell profiling of neural crest to identify key enhancers and transcription factors for cell fate competency, thus revealing progressive acquisition of fate potential.https://doi.org/10.1038/s41467-021-27594-w |
spellingShingle | Peter Fabian Kuo-Chang Tseng Mathi Thiruppathy Claire Arata Hung-Jhen Chen Joanna Smeeton Nellie Nelson J. Gage Crump Lifelong single-cell profiling of cranial neural crest diversification in zebrafish Nature Communications |
title | Lifelong single-cell profiling of cranial neural crest diversification in zebrafish |
title_full | Lifelong single-cell profiling of cranial neural crest diversification in zebrafish |
title_fullStr | Lifelong single-cell profiling of cranial neural crest diversification in zebrafish |
title_full_unstemmed | Lifelong single-cell profiling of cranial neural crest diversification in zebrafish |
title_short | Lifelong single-cell profiling of cranial neural crest diversification in zebrafish |
title_sort | lifelong single cell profiling of cranial neural crest diversification in zebrafish |
url | https://doi.org/10.1038/s41467-021-27594-w |
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