Granulomatous Neutrophilic Cystic Mastitis, Case Report
Cystic neutrophilic granulomatous mastitis (CNGM) is a recently characterized entity, with specific histopathological details that differentiate it from other types of chronic idiopathic mastitis. The presence of gram-positive bacilli within cystic-like spaces surrounded by neutrophils, in a context...
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| Format: | Article |
| Language: | Spanish |
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Universidad Ricardo Palma
2021-01-01
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| Series: | Revista de la Facultad de Medicina Humana |
| Subjects: | |
| Online Access: | http://revistas.urp.edu.pe/index.php/RFMH/article/view/3239 |
| _version_ | 1818556874025336832 |
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| author | Katherine Luisa Contreras Gala María del Carmen Kapsoli |
| author_facet | Katherine Luisa Contreras Gala María del Carmen Kapsoli |
| author_sort | Katherine Luisa Contreras Gala |
| collection | DOAJ |
| description | Cystic neutrophilic granulomatous mastitis (CNGM) is a recently characterized entity, with specific histopathological details that differentiate it from other types of chronic idiopathic mastitis. The presence of gram-positive bacilli within cystic-like spaces surrounded by neutrophils, in a context of suppurative granulomatous inflammation, define this entity. The importance of its recognition in the diagnostic report lies in its association with infection by corynebacterial species, so that treatment with antibiotics can be targeted, beyond the anti-inflammatory treatment that is usually administered to idiopathic mastitis. We describe the case of a 35-year-old female patient with no related history, with intermittent breast pain, associated with the presence of multiple hard, palpable nodules in both breasts, with results from multiple previous private biopsies that described chronic granulomatous mastitis with a tubercular reaction, for which she received treatment for tuberculosis. Despite this, the clinical response was partial. Histological slides were reviewed at the institution and the diagnosis of CNGM was then established. The presentation of this case was considered important due to its low recognition among pathologists, despite presenting characteristics already defined by previous studies. |
| first_indexed | 2024-12-13T23:52:51Z |
| format | Article |
| id | doaj.art-e49ec63663c940f589acc4fe619e00b7 |
| institution | Directory Open Access Journal |
| issn | 1814-5469 2308-0531 |
| language | Spanish |
| last_indexed | 2024-12-13T23:52:51Z |
| publishDate | 2021-01-01 |
| publisher | Universidad Ricardo Palma |
| record_format | Article |
| series | Revista de la Facultad de Medicina Humana |
| spelling | doaj.art-e49ec63663c940f589acc4fe619e00b72022-12-21T23:26:43ZspaUniversidad Ricardo PalmaRevista de la Facultad de Medicina Humana1814-54692308-05312021-01-0121119720110.25176/RFMH.v21i1.3239Granulomatous Neutrophilic Cystic Mastitis, Case ReportKatherine Luisa Contreras Galahttps://orcid.org/0000-0003-2140-6475María del Carmen Kapsolihttps://orcid.org/0000-0002-9882-3798Cystic neutrophilic granulomatous mastitis (CNGM) is a recently characterized entity, with specific histopathological details that differentiate it from other types of chronic idiopathic mastitis. The presence of gram-positive bacilli within cystic-like spaces surrounded by neutrophils, in a context of suppurative granulomatous inflammation, define this entity. The importance of its recognition in the diagnostic report lies in its association with infection by corynebacterial species, so that treatment with antibiotics can be targeted, beyond the anti-inflammatory treatment that is usually administered to idiopathic mastitis. We describe the case of a 35-year-old female patient with no related history, with intermittent breast pain, associated with the presence of multiple hard, palpable nodules in both breasts, with results from multiple previous private biopsies that described chronic granulomatous mastitis with a tubercular reaction, for which she received treatment for tuberculosis. Despite this, the clinical response was partial. Histological slides were reviewed at the institution and the diagnosis of CNGM was then established. The presentation of this case was considered important due to its low recognition among pathologists, despite presenting characteristics already defined by previous studies.http://revistas.urp.edu.pe/index.php/RFMH/article/view/3239cystic neutrophilic granulomatous mastitisgram-positive bacillicorynebacteriachronic mastitis |
| spellingShingle | Katherine Luisa Contreras Gala María del Carmen Kapsoli Granulomatous Neutrophilic Cystic Mastitis, Case Report Revista de la Facultad de Medicina Humana cystic neutrophilic granulomatous mastitis gram-positive bacilli corynebacteria chronic mastitis |
| title | Granulomatous Neutrophilic Cystic Mastitis, Case Report |
| title_full | Granulomatous Neutrophilic Cystic Mastitis, Case Report |
| title_fullStr | Granulomatous Neutrophilic Cystic Mastitis, Case Report |
| title_full_unstemmed | Granulomatous Neutrophilic Cystic Mastitis, Case Report |
| title_short | Granulomatous Neutrophilic Cystic Mastitis, Case Report |
| title_sort | granulomatous neutrophilic cystic mastitis case report |
| topic | cystic neutrophilic granulomatous mastitis gram-positive bacilli corynebacteria chronic mastitis |
| url | http://revistas.urp.edu.pe/index.php/RFMH/article/view/3239 |
| work_keys_str_mv | AT katherineluisacontrerasgala granulomatousneutrophiliccysticmastitiscasereport AT mariadelcarmenkapsoli granulomatousneutrophiliccysticmastitiscasereport |