Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines

Development of a highly reproducible system to evaluate inhibition of cytochrome P450 3A4 activity by natural medicines

PURPOSE: In recent years, a number of natural medicines have been reported to have inductive or inhibitive effects on the activity of drug metabolizing enzymes, upon co-administration with prescribed medicines. However, information regarding natural medicine-drug interactions that influence drug met...

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Bibliographic Details
Main Authors: Yu Sato, Takamitsu Sasaki, Shogo Takahashi, Takeshi Kumagai, Kiyoshi Nagata
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/24786

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