Demographic and clinical analysis on hospitalized patients with thrombocytopenia
Introduction: Thrombocytopenia is a common hematological abnormality observed in hospitalized patients. Objective: The present study was conducted to determine the prevalence of thrombocytopenia and its underlying causes. Patients and Methods: A retrospective analysis was performed on 221 thrombocyt...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Journal of Applied Hematology |
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| Online Access: | http://www.jahjournal.org/article.asp?issn=1658-5127;year=2014;volume=5;issue=2;spage=58;epage=64;aulast=Sajwani |
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| author | Fatma H Sajwani Hala O Al Tunaiji |
| author_facet | Fatma H Sajwani Hala O Al Tunaiji |
| author_sort | Fatma H Sajwani |
| collection | DOAJ |
| description | Introduction: Thrombocytopenia is a common hematological abnormality observed in hospitalized patients. Objective: The present study was conducted to determine the prevalence of thrombocytopenia and its underlying causes. Patients and Methods: A retrospective analysis was performed on 221 thrombocytopenia patients (platelet count <100 × 10 9 /L) admitted to a single center (Al Qassimi Hospital-United Arab Emirates, Sharjah) between the years 2005 and 2010, and the demographics, associated conditions, therapy and outcome assessed. Results: Median age at diagnosis was 39 years (range 0-90 years), including 18.5% children. The majority of patients presented with platelet counts ≥71 × 10 9 /L. Thrombocytopenia was more common in younger women (20-40 years); the proportion of men was greater in the elderly population. Thrombocytopenia was associated in 28.5% of the patients with infections, in 14% with pregnancy, in 10.4% with cardiac disease, in 10.0% with surgical interventions and in 7.7% with liver/kidney disease. Immune thrombocytopenia was diagnosed in 3.6% of the patients. Spontaneous recovery was observed for 72.5% of the untreated patients, and 71.9% of the patients receiving antibiotics to treat underlying infections subsequently recovered. Conclusion: The reason for low platelet counts may be multi-factorial for many patients and not restricted to a single underlying condition. Standard treatment options are generally effective, but newer treatment modalities may be explored for patients which fail to respond. |
| first_indexed | 2024-12-23T14:44:54Z |
| format | Article |
| id | doaj.art-e4a417e287fe4a55af03541ff094ed5f |
| institution | Directory Open Access Journal |
| issn | 1658-5127 |
| language | English |
| last_indexed | 2024-12-23T14:44:54Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Applied Hematology |
| spelling | doaj.art-e4a417e287fe4a55af03541ff094ed5f2022-12-21T17:43:07ZengWolters Kluwer Medknow PublicationsJournal of Applied Hematology1658-51272014-01-0152586410.4103/1658-5127.137147Demographic and clinical analysis on hospitalized patients with thrombocytopeniaFatma H SajwaniHala O Al TunaijiIntroduction: Thrombocytopenia is a common hematological abnormality observed in hospitalized patients. Objective: The present study was conducted to determine the prevalence of thrombocytopenia and its underlying causes. Patients and Methods: A retrospective analysis was performed on 221 thrombocytopenia patients (platelet count <100 × 10 9 /L) admitted to a single center (Al Qassimi Hospital-United Arab Emirates, Sharjah) between the years 2005 and 2010, and the demographics, associated conditions, therapy and outcome assessed. Results: Median age at diagnosis was 39 years (range 0-90 years), including 18.5% children. The majority of patients presented with platelet counts ≥71 × 10 9 /L. Thrombocytopenia was more common in younger women (20-40 years); the proportion of men was greater in the elderly population. Thrombocytopenia was associated in 28.5% of the patients with infections, in 14% with pregnancy, in 10.4% with cardiac disease, in 10.0% with surgical interventions and in 7.7% with liver/kidney disease. Immune thrombocytopenia was diagnosed in 3.6% of the patients. Spontaneous recovery was observed for 72.5% of the untreated patients, and 71.9% of the patients receiving antibiotics to treat underlying infections subsequently recovered. Conclusion: The reason for low platelet counts may be multi-factorial for many patients and not restricted to a single underlying condition. Standard treatment options are generally effective, but newer treatment modalities may be explored for patients which fail to respond.http://www.jahjournal.org/article.asp?issn=1658-5127;year=2014;volume=5;issue=2;spage=58;epage=64;aulast=SajwaniCardiac diseaseplatelet countsthrombocytopenia |
| spellingShingle | Fatma H Sajwani Hala O Al Tunaiji Demographic and clinical analysis on hospitalized patients with thrombocytopenia Journal of Applied Hematology Cardiac disease platelet counts thrombocytopenia |
| title | Demographic and clinical analysis on hospitalized patients with thrombocytopenia |
| title_full | Demographic and clinical analysis on hospitalized patients with thrombocytopenia |
| title_fullStr | Demographic and clinical analysis on hospitalized patients with thrombocytopenia |
| title_full_unstemmed | Demographic and clinical analysis on hospitalized patients with thrombocytopenia |
| title_short | Demographic and clinical analysis on hospitalized patients with thrombocytopenia |
| title_sort | demographic and clinical analysis on hospitalized patients with thrombocytopenia |
| topic | Cardiac disease platelet counts thrombocytopenia |
| url | http://www.jahjournal.org/article.asp?issn=1658-5127;year=2014;volume=5;issue=2;spage=58;epage=64;aulast=Sajwani |
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