A Strategy for Uncovering the Serum Metabolome by Direct-Infusion High-Resolution Mass Spectrometry

A Strategy for Uncovering the Serum Metabolome by Direct-Infusion High-Resolution Mass Spectrometry

Direct infusion nanoelectrospray high-resolution mass spectrometry (DI-nESI-HRMS) is a promising tool for high-throughput metabolomics analysis. However, metabolite assignment is limited by the inadequate mass accuracy and chemical space of the metabolome database. Here, a serum metabolome character...

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Bibliographic Details
Main Authors: Xiaoshan Sun, Zhen Jia, Yuqing Zhang, Xinjie Zhao, Chunxia Zhao, Xin Lu, Guowang Xu
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Metabolites
Subjects:
metabolomics
direct-infusion
high-resolution mass spectrometry
formula assignment
reaction network
Online Access:https://www.mdpi.com/2218-1989/13/3/460

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