Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative Review
Premature birth is a major cause of mortality and morbidity in the pediatric population. Because their immune, gastrointestinal and nervous systems are not fully developed, preterm infants (<37 weeks of gestation) and especially very preterm infants (VPIs, <32 weeks of gestation) are more pron...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/9/2208 |
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| author | Margarita Dimitroglou Zoi Iliodromiti Evangelos Christou Paraskevi Volaki Chrysa Petropoulou Rozeta Sokou Theodora Boutsikou Nicoletta Iacovidou |
| author_facet | Margarita Dimitroglou Zoi Iliodromiti Evangelos Christou Paraskevi Volaki Chrysa Petropoulou Rozeta Sokou Theodora Boutsikou Nicoletta Iacovidou |
| author_sort | Margarita Dimitroglou |
| collection | DOAJ |
| description | Premature birth is a major cause of mortality and morbidity in the pediatric population. Because their immune, gastrointestinal and nervous systems are not fully developed, preterm infants (<37 weeks of gestation) and especially very preterm infants (VPIs, <32 weeks of gestation) are more prone to infectious diseases, tissue damage and future neurodevelopmental impairment. The aim of this narrative review is to report the immaturity of VPI systems and examine the role of Human Breast Milk (HBM) in their development and protection against infectious diseases, inflammation and tissue damage. For this purpose, we searched and synthesized the data from the existing literature published in the English language. Studies revealed the significance of HBM and indicate HBM as the best dietary choice for VPIs. |
| first_indexed | 2024-03-10T00:17:25Z |
| format | Article |
| id | doaj.art-e4a634ce707f460391ce5906ba01e40c |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-10T00:17:25Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-e4a634ce707f460391ce5906ba01e40c2023-11-23T15:50:28ZengMDPI AGDiagnostics2075-44182022-09-01129220810.3390/diagnostics12092208Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative ReviewMargarita Dimitroglou0Zoi Iliodromiti1Evangelos Christou2Paraskevi Volaki3Chrysa Petropoulou4Rozeta Sokou5Theodora Boutsikou6Nicoletta Iacovidou7Neonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, GreeceNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, GreeceNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, GreeceNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, GreeceNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, GreeceNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, GreeceNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, GreeceNeonatal Department, Medical School, National and Kapodistrian University of Athens, Aretaieio Hospital, 11528 Athens, GreecePremature birth is a major cause of mortality and morbidity in the pediatric population. Because their immune, gastrointestinal and nervous systems are not fully developed, preterm infants (<37 weeks of gestation) and especially very preterm infants (VPIs, <32 weeks of gestation) are more prone to infectious diseases, tissue damage and future neurodevelopmental impairment. The aim of this narrative review is to report the immaturity of VPI systems and examine the role of Human Breast Milk (HBM) in their development and protection against infectious diseases, inflammation and tissue damage. For this purpose, we searched and synthesized the data from the existing literature published in the English language. Studies revealed the significance of HBM and indicate HBM as the best dietary choice for VPIs.https://www.mdpi.com/2075-4418/12/9/2208breast milkimmune systemgastrointestinal systemcentral nervous systemneonate |
| spellingShingle | Margarita Dimitroglou Zoi Iliodromiti Evangelos Christou Paraskevi Volaki Chrysa Petropoulou Rozeta Sokou Theodora Boutsikou Nicoletta Iacovidou Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative Review Diagnostics breast milk immune system gastrointestinal system central nervous system neonate |
| title | Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative Review |
| title_full | Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative Review |
| title_fullStr | Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative Review |
| title_full_unstemmed | Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative Review |
| title_short | Human Breast Milk: The Key Role in the Maturation of Immune, Gastrointestinal and Central Nervous Systems: A Narrative Review |
| title_sort | human breast milk the key role in the maturation of immune gastrointestinal and central nervous systems a narrative review |
| topic | breast milk immune system gastrointestinal system central nervous system neonate |
| url | https://www.mdpi.com/2075-4418/12/9/2208 |
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