Bitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in Chickens
Canola meal (CM) is a commonly used feedstuff; however, it is known to be bitter, and chickens have a low preference for it. The purpose of this study was to seek clarity regarding the taste quality of CM and find methods to increase the preference for CM by chickens. We examined whether CM activate...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Japan Poultry Science Association
2020-07-01
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| Series: | The Journal of Poultry Science |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jpsa/57/3/57_0190099/_html/-char/en |
| _version_ | 1797817089209139200 |
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| author | Fuminori Kawabata Bapon Dey Yuta Yoshida Shotaro Nishimura Shoji Tabata |
| author_facet | Fuminori Kawabata Bapon Dey Yuta Yoshida Shotaro Nishimura Shoji Tabata |
| author_sort | Fuminori Kawabata |
| collection | DOAJ |
| description | Canola meal (CM) is a commonly used feedstuff; however, it is known to be bitter, and chickens have a low preference for it. The purpose of this study was to seek clarity regarding the taste quality of CM and find methods to increase the preference for CM by chickens. We examined whether CM activates the bitter taste receptors in chickens, whether chickens show aversive responses to CM, and whether an antagonist for bitter taste receptors inhibits the bitterness of CM. Using the Ca2+ imaging technique, we showed that CM contains bitter compounds, which activate the bitter taste receptors in chickens. Further, we showed that 6-methoxyflavanone (6-meth), an antagonist for the bitter taste receptors in chickens, inhibits the activation of these receptors by CM extract. Although chickens showed a low preference for the solution of the CM extract, their preference was improved by adding 6-meth in behavioral tests. These results suggest that the preference for CM could be improved by inhibiting the bitter taste receptors in chickens. |
| first_indexed | 2024-03-13T08:47:34Z |
| format | Article |
| id | doaj.art-e4a6df49d17a486ab2fd376acdae0787 |
| institution | Directory Open Access Journal |
| issn | 1346-7395 1349-0486 |
| language | English |
| last_indexed | 2024-03-13T08:47:34Z |
| publishDate | 2020-07-01 |
| publisher | Japan Poultry Science Association |
| record_format | Article |
| series | The Journal of Poultry Science |
| spelling | doaj.art-e4a6df49d17a486ab2fd376acdae07872023-05-30T01:12:51ZengJapan Poultry Science AssociationThe Journal of Poultry Science1346-73951349-04862020-07-0157322322810.2141/jpsa.0190099jpsaBitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in ChickensFuminori Kawabata0Bapon Dey1Yuta Yoshida2Shotaro Nishimura3Shoji Tabata4Laboratory of Functional Anatomy, Faculty of Agriculture, Kyushu UniversityLaboratory of Functional Anatomy, Faculty of Agriculture, Kyushu UniversityLaboratory of Functional Anatomy, Faculty of Agriculture, Kyushu UniversityLaboratory of Functional Anatomy, Faculty of Agriculture, Kyushu UniversityLaboratory of Functional Anatomy, Faculty of Agriculture, Kyushu UniversityCanola meal (CM) is a commonly used feedstuff; however, it is known to be bitter, and chickens have a low preference for it. The purpose of this study was to seek clarity regarding the taste quality of CM and find methods to increase the preference for CM by chickens. We examined whether CM activates the bitter taste receptors in chickens, whether chickens show aversive responses to CM, and whether an antagonist for bitter taste receptors inhibits the bitterness of CM. Using the Ca2+ imaging technique, we showed that CM contains bitter compounds, which activate the bitter taste receptors in chickens. Further, we showed that 6-methoxyflavanone (6-meth), an antagonist for the bitter taste receptors in chickens, inhibits the activation of these receptors by CM extract. Although chickens showed a low preference for the solution of the CM extract, their preference was improved by adding 6-meth in behavioral tests. These results suggest that the preference for CM could be improved by inhibiting the bitter taste receptors in chickens.https://www.jstage.jst.go.jp/article/jpsa/57/3/57_0190099/_html/-char/enbitter taste receptorcanola mealchicken |
| spellingShingle | Fuminori Kawabata Bapon Dey Yuta Yoshida Shotaro Nishimura Shoji Tabata Bitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in Chickens The Journal of Poultry Science bitter taste receptor canola meal chicken |
| title | Bitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in Chickens |
| title_full | Bitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in Chickens |
| title_fullStr | Bitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in Chickens |
| title_full_unstemmed | Bitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in Chickens |
| title_short | Bitter Taste Receptor Antagonists Inhibit the Bitter taste of Canola Meal Extract in Chickens |
| title_sort | bitter taste receptor antagonists inhibit the bitter taste of canola meal extract in chickens |
| topic | bitter taste receptor canola meal chicken |
| url | https://www.jstage.jst.go.jp/article/jpsa/57/3/57_0190099/_html/-char/en |
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