Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic Tool
The current screening test for prostate cancer (PCa) has the weak point of a high false-negative rate and a low true positive rate. There is an extreme need for a new and accurate testing system. Circulating Tumor Cells (CTCs) as the main liquid biopsy components provide excellent biomarkers for ear...
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| Format: | Article |
| Language: | English |
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Urology Research Center
2020-08-01
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| Series: | Translational Research in Urology |
| Subjects: | |
| Online Access: | https://www.transresurology.com/article_120191.html |
| _version_ | 1819005493294661632 |
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| author | Fatemeh Khatami Mandana Hasanzad |
| author_facet | Fatemeh Khatami Mandana Hasanzad |
| author_sort | Fatemeh Khatami |
| collection | DOAJ |
| description | The current screening test for prostate cancer (PCa) has the weak point of a high false-negative rate and a low true positive rate. There is an extreme need for a new and accurate testing system. Circulating Tumor Cells (CTCs) as the main liquid biopsy components provide excellent biomarkers for early diagnosis of PCa, prognosis, recurrence risk, and treatment efficacy. These tumor cells can get the release of tumor and freely circulate in the patient’s body fluids and easily are traceable to answer the presence of the tumor more than its stage. The new gifted ISET®-CTC Test is a simple blood test with high sensitivity and specificity for the detection of CTC in PCa. As a novel idea, it is a challengeable point nowadays that it needs further studies. |
| first_indexed | 2024-12-20T23:53:40Z |
| format | Article |
| id | doaj.art-e4a7a1e2bb81432fba647a281a2133e2 |
| institution | Directory Open Access Journal |
| issn | 2717-042X |
| language | English |
| last_indexed | 2024-12-20T23:53:40Z |
| publishDate | 2020-08-01 |
| publisher | Urology Research Center |
| record_format | Article |
| series | Translational Research in Urology |
| spelling | doaj.art-e4a7a1e2bb81432fba647a281a2133e22022-12-21T19:22:47ZengUrology Research CenterTranslational Research in Urology2717-042X2020-08-0123939510.22034/TRU.2020.260779.1055Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic ToolFatemeh Khatami 0Mandana Hasanzad1Urology Research Center, Tehran University of Medical Sciences, Tehran, IranMedical Genomics Research Center, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, IranThe current screening test for prostate cancer (PCa) has the weak point of a high false-negative rate and a low true positive rate. There is an extreme need for a new and accurate testing system. Circulating Tumor Cells (CTCs) as the main liquid biopsy components provide excellent biomarkers for early diagnosis of PCa, prognosis, recurrence risk, and treatment efficacy. These tumor cells can get the release of tumor and freely circulate in the patient’s body fluids and easily are traceable to answer the presence of the tumor more than its stage. The new gifted ISET®-CTC Test is a simple blood test with high sensitivity and specificity for the detection of CTC in PCa. As a novel idea, it is a challengeable point nowadays that it needs further studies.https://www.transresurology.com/article_120191.htmlcirculating tumor cellsprostate cancerbenign prostatic hyperplasia |
| spellingShingle | Fatemeh Khatami Mandana Hasanzad Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic Tool Translational Research in Urology circulating tumor cells prostate cancer benign prostatic hyperplasia |
| title | Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic Tool |
| title_full | Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic Tool |
| title_fullStr | Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic Tool |
| title_full_unstemmed | Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic Tool |
| title_short | Circulating Tumor Cells as a Novel Prostate Cancer Diagnostic Tool |
| title_sort | circulating tumor cells as a novel prostate cancer diagnostic tool |
| topic | circulating tumor cells prostate cancer benign prostatic hyperplasia |
| url | https://www.transresurology.com/article_120191.html |
| work_keys_str_mv | AT fatemehkhatami circulatingtumorcellsasanovelprostatecancerdiagnostictool AT mandanahasanzad circulatingtumorcellsasanovelprostatecancerdiagnostictool |