Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism

Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism

BackgroundThe genetic predisposition to elite athletic performance has been a controversial subject due to the underpowered studies and the small effect size of identified genetic variants. The aims of this study were to investigate the association of common single-nucleotide polymorphisms (SNPs) wi...

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Main Authors: Fatima Al-Khelaifi, Noha A. Yousri, Ilhame Diboun, Ekaterina A. Semenova, Elena S. Kostryukova, Nikolay A. Kulemin, Oleg V. Borisov, Liliya B. Andryushchenko, Andrey K. Larin, Edward V. Generozov, Eri Miyamoto-Mikami, Haruka Murakami, Hirofumi Zempo, Motohiko Miyachi, Mizuki Takaragawa, Hiroshi Kumagai, Hisashi Naito, Noriyuki Fuku, David Abraham, Aroon Hingorani, Francesco Donati, Francesco Botrè, Costas Georgakopoulos, Karsten Suhre, Ildus I. Ahmetov, Omar Albagha, Mohamed A. Elrayess
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
GWAS
SNP
metabolomics
metabolites
elite athletes
endurance
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00595/full

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