Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature review

Herlyn-Werner-Wunderlich syndrome, is a rare urogenital congenital anomaly. Coexisting Mullerian ducts anomalies and ovarian neoplasms are rarely reported. We present the first case of Herlyn-Werner-Wunderlich syndrome with borderline serous neoplasm of the ovary. A 29-year-old married female with p...

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Main Authors: Johara AlMulhim, MD, Mohannad Rasheed AlRasheed, MD
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Radiology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043320305124
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author Johara AlMulhim, MD
Mohannad Rasheed AlRasheed, MD
author_facet Johara AlMulhim, MD
Mohannad Rasheed AlRasheed, MD
author_sort Johara AlMulhim, MD
collection DOAJ
description Herlyn-Werner-Wunderlich syndrome, is a rare urogenital congenital anomaly. Coexisting Mullerian ducts anomalies and ovarian neoplasms are rarely reported. We present the first case of Herlyn-Werner-Wunderlich syndrome with borderline serous neoplasm of the ovary. A 29-year-old married female with primary infertility and elevated level of cancer antigen 125 (CA-125), underwent pelvic magnetic resonance imaging for evaluation which revealed uterus didelphys, obstructed right hemivagina, right renal agenesis as well as right ovarian cystic lesion. Ovary preserving laparoscopic cystectomy was performed with a pathological diagnosis of a serous borderline tumor. Although rarely reported, Mullerian ducts anomalies and uterine or ovarian remnant neoplasms can occur. These few case reports may suggest an underlying, yet to be discovered, genetic association of Mullerian ducts anomalies and development of ovarian neoplasms of various pathological subtypes.
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spelling doaj.art-e4a8cf4d007941b39f62448156c0af6c2022-12-21T23:15:01ZengElsevierRadiology Case Reports1930-04332021-03-01163744747Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature reviewJohara AlMulhim, MD0Mohannad Rasheed AlRasheed, MD1College of Medicine, King Faisal University, 4008, Hofuf, Ahsa, Saudi Arabia; Corresponding author.Department of Medical Imaging, Prince Sultan Military Medical City, Riyadh, Saudi ArabiaHerlyn-Werner-Wunderlich syndrome, is a rare urogenital congenital anomaly. Coexisting Mullerian ducts anomalies and ovarian neoplasms are rarely reported. We present the first case of Herlyn-Werner-Wunderlich syndrome with borderline serous neoplasm of the ovary. A 29-year-old married female with primary infertility and elevated level of cancer antigen 125 (CA-125), underwent pelvic magnetic resonance imaging for evaluation which revealed uterus didelphys, obstructed right hemivagina, right renal agenesis as well as right ovarian cystic lesion. Ovary preserving laparoscopic cystectomy was performed with a pathological diagnosis of a serous borderline tumor. Although rarely reported, Mullerian ducts anomalies and uterine or ovarian remnant neoplasms can occur. These few case reports may suggest an underlying, yet to be discovered, genetic association of Mullerian ducts anomalies and development of ovarian neoplasms of various pathological subtypes.http://www.sciencedirect.com/science/article/pii/S1930043320305124Congenital anomaliesKidneysOvarian neoplasms
spellingShingle Johara AlMulhim, MD
Mohannad Rasheed AlRasheed, MD
Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature review
Radiology Case Reports
Congenital anomalies
Kidneys
Ovarian neoplasms
title Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature review
title_full Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature review
title_fullStr Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature review
title_full_unstemmed Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature review
title_short Herlyn-Werner-Wunderlich syndrome with borderline serous cystadenoma of the ovary: case report and literature review
title_sort herlyn werner wunderlich syndrome with borderline serous cystadenoma of the ovary case report and literature review
topic Congenital anomalies
Kidneys
Ovarian neoplasms
url http://www.sciencedirect.com/science/article/pii/S1930043320305124
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