Diosgenin protects against cationic bovine serum albumin-induced membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via the NF-κB pathway

Diosgenin protects against cationic bovine serum albumin-induced membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via the NF-κB pathway

AbstractContext Membranous glomerulonephritis (MGN) is a leading cause of nephrotic syndrome in adults. Diosgenin (DG) has been reported to exert antioxidative and anti-inflammatory effects.Objective To investigate the renoprotective activity of DG in a cationic bovine serum albumin-induced rat mode...

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Bibliographic Details
Main Authors:	Shiyan Jia, Ruihua Si, Guangzhen Liu, Qiming Zhong
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Series:	Pharmaceutical Biology
Subjects:	Chronic kidney disease podocyte traditional Chinese medicine Nrf2/Keap1 signalling pathway
Online Access:	https://www.tandfonline.com/doi/10.1080/13880209.2024.2330602

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