Role of oral zinc sulphate in warts-a placebo controlled,single-blinded study

Verrucae (synonym: warts) are one of the most common viral infections of humans in which the most frequently used modalities of treatment involve destruction of the affected area, which does not prevent recurrences and often results in scarring. In the present study oral zinc sulphate, an immunomodu...

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Main Authors: Iffat Hassan, Taseer Bhat, Hinah Altaf, Farah Sameem, Qazi Masood
Format: Article
Language:English
Published: Our Dermatology Online 2013-01-01
Series:Nasza Dermatologia Online
Subjects:
Online Access:http://www.odermatol.com/issue-in-html/2013-1-4-role/
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author Iffat Hassan
Taseer Bhat
Hinah Altaf
Farah Sameem
Qazi Masood
author_facet Iffat Hassan
Taseer Bhat
Hinah Altaf
Farah Sameem
Qazi Masood
author_sort Iffat Hassan
collection DOAJ
description Verrucae (synonym: warts) are one of the most common viral infections of humans in which the most frequently used modalities of treatment involve destruction of the affected area, which does not prevent recurrences and often results in scarring. In the present study oral zinc sulphate, an immunomodulator was evaluated as a treatment modality for warts. A placebo-controlled, single-blinded study was conducted on one hundred OPD patients with various types of verrucae. Fifty patients were put on oral zinc sulphate at dose of 5mg/kg for six weeks, while an equal number of patients received placebo for the same duration. In the patients who received oral zinc sulphate, 60.97% showed complete response at the end of six weeks in comparison to 6.45% partial response in the placebo group. The resolution of the lesions occurred with restoration of normal epidermal texture with transient alteration in pigmentation.
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spelling doaj.art-e4abb712bd6f4950b88ea80abc2e147e2022-12-21T19:10:37ZengOur Dermatology OnlineNasza Dermatologia Online2081-93902013-01-01412427Role of oral zinc sulphate in warts-a placebo controlled,single-blinded studyIffat HassanTaseer BhatHinah AltafFarah SameemQazi MasoodVerrucae (synonym: warts) are one of the most common viral infections of humans in which the most frequently used modalities of treatment involve destruction of the affected area, which does not prevent recurrences and often results in scarring. In the present study oral zinc sulphate, an immunomodulator was evaluated as a treatment modality for warts. A placebo-controlled, single-blinded study was conducted on one hundred OPD patients with various types of verrucae. Fifty patients were put on oral zinc sulphate at dose of 5mg/kg for six weeks, while an equal number of patients received placebo for the same duration. In the patients who received oral zinc sulphate, 60.97% showed complete response at the end of six weeks in comparison to 6.45% partial response in the placebo group. The resolution of the lesions occurred with restoration of normal epidermal texture with transient alteration in pigmentation.http://www.odermatol.com/issue-in-html/2013-1-4-role/verrucaezinc sulphatehuman papillomavirus
spellingShingle Iffat Hassan
Taseer Bhat
Hinah Altaf
Farah Sameem
Qazi Masood
Role of oral zinc sulphate in warts-a placebo controlled,single-blinded study
Nasza Dermatologia Online
verrucae
zinc sulphate
human papillomavirus
title Role of oral zinc sulphate in warts-a placebo controlled,single-blinded study
title_full Role of oral zinc sulphate in warts-a placebo controlled,single-blinded study
title_fullStr Role of oral zinc sulphate in warts-a placebo controlled,single-blinded study
title_full_unstemmed Role of oral zinc sulphate in warts-a placebo controlled,single-blinded study
title_short Role of oral zinc sulphate in warts-a placebo controlled,single-blinded study
title_sort role of oral zinc sulphate in warts a placebo controlled single blinded study
topic verrucae
zinc sulphate
human papillomavirus
url http://www.odermatol.com/issue-in-html/2013-1-4-role/
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AT farahsameem roleoforalzincsulphateinwartsaplacebocontrolledsingleblindedstudy
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