Improved prediction of MHC-peptide binding using protein language models
Major histocompatibility complex Class I (MHC-I) molecules bind to peptides derived from intracellular antigens and present them on the surface of cells, allowing the immune system (T cells) to detect them. Elucidating the process of this presentation is essential for regulation and potential manipu...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-08-01
|
Series: | Frontiers in Bioinformatics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbinf.2023.1207380/full |