Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium Tetrachloride
Abstract A biomimetic iodofunctionalization of aromatic and heteroaromatic compounds has been developed using NaI as a source of iodine and 30% H2O2 as a mild oxidant, as well as SeCl4 as a commercially available catalyst in water without a co-solvent. The method affords iodinated compounds in isola...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2019-10-01
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| Series: | SynOpen |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1690337 |
| _version_ | 1818932256944685056 |
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| author | Beatriz C. O. Rocha Givago P. Perecim Cristiano Raminelli |
| author_facet | Beatriz C. O. Rocha Givago P. Perecim Cristiano Raminelli |
| author_sort | Beatriz C. O. Rocha |
| collection | DOAJ |
| description | Abstract
A biomimetic iodofunctionalization of aromatic and heteroaromatic compounds has been developed using NaI as a source of iodine and 30% H2O2 as a mild oxidant, as well as SeCl4 as a commercially available catalyst in water without a co-solvent. The method affords iodinated compounds in isolated yields of 37 to 99%. The catalytic system has potential for the bromination of aromatic substrates. |
| first_indexed | 2024-12-20T04:29:36Z |
| format | Article |
| id | doaj.art-e4aebf73572e46a1975e11267bfbd93a |
| institution | Directory Open Access Journal |
| issn | 2509-9396 |
| language | English |
| last_indexed | 2024-12-20T04:29:36Z |
| publishDate | 2019-10-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | SynOpen |
| spelling | doaj.art-e4aebf73572e46a1975e11267bfbd93a2022-12-21T19:53:26ZengGeorg Thieme Verlag KGSynOpen2509-93962019-10-01030414214710.1055/s-0039-1690337Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium TetrachlorideBeatriz C. O. RochaGivago P. PerecimCristiano Raminelli0Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São PauloAbstract A biomimetic iodofunctionalization of aromatic and heteroaromatic compounds has been developed using NaI as a source of iodine and 30% H2O2 as a mild oxidant, as well as SeCl4 as a commercially available catalyst in water without a co-solvent. The method affords iodinated compounds in isolated yields of 37 to 99%. The catalytic system has potential for the bromination of aromatic substrates.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1690337biomimetic synthesisiodofunctionalizationselenium catalysisiodinationaqueous reaction |
| spellingShingle | Beatriz C. O. Rocha Givago P. Perecim Cristiano Raminelli Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium Tetrachloride SynOpen biomimetic synthesis iodofunctionalization selenium catalysis iodination aqueous reaction |
| title | Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium Tetrachloride |
| title_full | Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium Tetrachloride |
| title_fullStr | Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium Tetrachloride |
| title_full_unstemmed | Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium Tetrachloride |
| title_short | Biomimetic Iodofunctionalization of Aromatic and Heteroaromatic Compounds Catalyzed by Selenium Tetrachloride |
| title_sort | biomimetic iodofunctionalization of aromatic and heteroaromatic compounds catalyzed by selenium tetrachloride |
| topic | biomimetic synthesis iodofunctionalization selenium catalysis iodination aqueous reaction |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1690337 |
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