Defective Interfering Particles of Influenza Virus and Their Characteristics, Impacts, and Use in Vaccines and Antiviral Strategies: A Systematic Review

Defective Interfering Particles of Influenza Virus and Their Characteristics, Impacts, and Use in Vaccines and Antiviral Strategies: A Systematic Review

Defective interfering particles (DIPs) are particles containing defective viral genomes (DVGs) generated during viral replication. DIPs have been found in various RNA viruses, especially in influenza viruses. Evidence indicates that DIPs interfere with the replication and encapsulation of wild-type...

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Bibliographic Details
Main Authors: Min Wu, Entong Zhou, Rui Sheng, Xiaoshu Fu, Jiemin Li, Chunlai Jiang, Weiheng Su
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Viruses
Subjects:
defective interfering particles
defective viral genomes
influenza virus
viral replication
interferon
NS1
Online Access:https://www.mdpi.com/1999-4915/14/12/2773

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