Relationship between intraocular pressure and parameters of obesity in ocular hypertension
AIM: To evaluate the correlation between intraocular pressure (IOP) and various obesity-related health factors in patients with ocular hypertension in Korea. METHODS: A total of 40 850 subjects underwent age, sex, body weight, and height assessments and automated multiphasic tests, including non-co...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2020-05-01
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| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.cn/en_publish/2020/5/20200515.pdf |
| _version_ | 1818328717532856320 |
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| author | Min Won Ahn Ji Woong Lee Jong Hoon Shin Jong Soo Lee |
| author_facet | Min Won Ahn Ji Woong Lee Jong Hoon Shin Jong Soo Lee |
| author_sort | Min Won Ahn |
| collection | DOAJ |
| description | AIM: To evaluate the correlation between intraocular pressure (IOP) and various obesity-related health factors in patients with ocular hypertension in Korea.
METHODS: A total of 40 850 subjects underwent age, sex, body weight, and height assessments and automated multiphasic tests, including non-contact tonometry, automated perimetry, fundus photography, systolic/diastolic blood pressure measurement, and evaluation of obesity-related health parameters such as obesity index, body mass index (BMI), a body shape index (ABSI), and waist-to-height ratio (WtHR). Subjects were divided into ocular hypertension group and normal IOP group according to IOP after matching of age and sex.
RESULTS: Of 40 850 participants, 1515 (3.7%) had ocular hypertension, and 1515 with normal IOP were selected as controls using propensity score matching. The mean IOP of control group was 15.3±2.3 mm Hg, compared with 23.3±1.6 mm Hg in ocular hypertension group. Height, obesity index, BMI, and WtHR in the ocular hypertension group were significantly higher than in the normal IOP group (P<0.001, P<0.001, P=0.009, P=0.002). IOP of ocular hypertension was positively correlated with obesity index (P=0.027) and BMI (P=0.016), whereas IOP of control was positively correlated with blood pressure (P<0.001, P=0.002), obesity index (P<0.001), BMI (P<0.001), and WHtR (P=0.002). Systolic blood pressure (β=0.022, P<0.001) and body weight (β=0.016, P=0.02) were precursors of IOP in normal subjects, but sex (male; β=-0.231, P=0.008) and obesity index (β=-0.007, P=0.017) were precursors of ocular hypertension according to multiple regression analysis .
CONCLUSION: Among various obesity-related health parameters, obesity index is the best indicator for further increase in IOP in ocular hypertension group. |
| first_indexed | 2024-12-13T12:36:36Z |
| format | Article |
| id | doaj.art-e4afd2dfc8dd41c4b8955c64bc1d4fa7 |
| institution | Directory Open Access Journal |
| issn | 2222-3959 2227-4898 |
| language | English |
| last_indexed | 2024-12-13T12:36:36Z |
| publishDate | 2020-05-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj.art-e4afd2dfc8dd41c4b8955c64bc1d4fa72022-12-21T23:45:49ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982020-05-0113579480010.18240/ijo.2020.05.15Relationship between intraocular pressure and parameters of obesity in ocular hypertensionMin Won Ahn0Ji Woong Lee1Jong Hoon Shin2Jong Soo Lee3Busan Sungmo Eye Hospital, Busan 48064, KoreaDepartment of Ophthalmology, Pusan National University College of Medicine and Medical Research Institute of Pusan National University Hospital, Busan 49241, KoreaDepartment of Ophthalmology, Pusan National University Yangsan Hospital, Yangsan 50612, KoreaDepartment of Ophthalmology, Pusan National University College of Medicine and Medical Research Institute of Pusan National University Hospital, Busan 49241, KoreaAIM: To evaluate the correlation between intraocular pressure (IOP) and various obesity-related health factors in patients with ocular hypertension in Korea. METHODS: A total of 40 850 subjects underwent age, sex, body weight, and height assessments and automated multiphasic tests, including non-contact tonometry, automated perimetry, fundus photography, systolic/diastolic blood pressure measurement, and evaluation of obesity-related health parameters such as obesity index, body mass index (BMI), a body shape index (ABSI), and waist-to-height ratio (WtHR). Subjects were divided into ocular hypertension group and normal IOP group according to IOP after matching of age and sex. RESULTS: Of 40 850 participants, 1515 (3.7%) had ocular hypertension, and 1515 with normal IOP were selected as controls using propensity score matching. The mean IOP of control group was 15.3±2.3 mm Hg, compared with 23.3±1.6 mm Hg in ocular hypertension group. Height, obesity index, BMI, and WtHR in the ocular hypertension group were significantly higher than in the normal IOP group (P<0.001, P<0.001, P=0.009, P=0.002). IOP of ocular hypertension was positively correlated with obesity index (P=0.027) and BMI (P=0.016), whereas IOP of control was positively correlated with blood pressure (P<0.001, P=0.002), obesity index (P<0.001), BMI (P<0.001), and WHtR (P=0.002). Systolic blood pressure (β=0.022, P<0.001) and body weight (β=0.016, P=0.02) were precursors of IOP in normal subjects, but sex (male; β=-0.231, P=0.008) and obesity index (β=-0.007, P=0.017) were precursors of ocular hypertension according to multiple regression analysis . CONCLUSION: Among various obesity-related health parameters, obesity index is the best indicator for further increase in IOP in ocular hypertension group.http://www.ijo.cn/en_publish/2020/5/20200515.pdfintraocular pressureocular hypertensionbody mass indexbody shape indexwaist-to-height ratio |
| spellingShingle | Min Won Ahn Ji Woong Lee Jong Hoon Shin Jong Soo Lee Relationship between intraocular pressure and parameters of obesity in ocular hypertension International Journal of Ophthalmology intraocular pressure ocular hypertension body mass index body shape index waist-to-height ratio |
| title | Relationship between intraocular pressure and parameters of obesity in ocular hypertension |
| title_full | Relationship between intraocular pressure and parameters of obesity in ocular hypertension |
| title_fullStr | Relationship between intraocular pressure and parameters of obesity in ocular hypertension |
| title_full_unstemmed | Relationship between intraocular pressure and parameters of obesity in ocular hypertension |
| title_short | Relationship between intraocular pressure and parameters of obesity in ocular hypertension |
| title_sort | relationship between intraocular pressure and parameters of obesity in ocular hypertension |
| topic | intraocular pressure ocular hypertension body mass index body shape index waist-to-height ratio |
| url | http://www.ijo.cn/en_publish/2020/5/20200515.pdf |
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