Complements from the Male Reproductive Tract: A Scoping Review

The organs of the male reproductive tract, including the testis, epididymis, prostate, seminal vesicles, and semen, must provide an immunoregulatory environment conducive to germ cell viability and successful fertilization. Many immune components, such as immune cells, have been investigated regardi...

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Main Author: Rachel L. Washburn
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:BioMed
Subjects:
Online Access:https://www.mdpi.com/2673-8430/4/1/2
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author Rachel L. Washburn
author_facet Rachel L. Washburn
author_sort Rachel L. Washburn
collection DOAJ
description The organs of the male reproductive tract, including the testis, epididymis, prostate, seminal vesicles, and semen, must provide an immunoregulatory environment conducive to germ cell viability and successful fertilization. Many immune components, such as immune cells, have been investigated regarding reproductive immunology and function; however, the investigation of the role of complement in this system has only more recently been gaining traction in research. This review focuses on complement in the male reproductive tract, with the goal of compiling information currently known about complement components detected in male reproductive organs and identifying areas in need of further research. Considering the recent and upcoming research about the noncanonical functions of complement, this information is relevant and applicable in the fields of reproductive immunology, fertility, and immune regulation.
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spelling doaj.art-e4b184b240a243b185599288ae0a9d422024-03-27T13:22:24ZengMDPI AGBioMed2673-84302024-01-0141193810.3390/biomed4010002Complements from the Male Reproductive Tract: A Scoping ReviewRachel L. Washburn0Department of Life and Physical Sciences, School of Arts, Sciences and Education, Ivy Tech Community College, 8204 County Rd. 311, Sellersburg, IN 47172, USAThe organs of the male reproductive tract, including the testis, epididymis, prostate, seminal vesicles, and semen, must provide an immunoregulatory environment conducive to germ cell viability and successful fertilization. Many immune components, such as immune cells, have been investigated regarding reproductive immunology and function; however, the investigation of the role of complement in this system has only more recently been gaining traction in research. This review focuses on complement in the male reproductive tract, with the goal of compiling information currently known about complement components detected in male reproductive organs and identifying areas in need of further research. Considering the recent and upcoming research about the noncanonical functions of complement, this information is relevant and applicable in the fields of reproductive immunology, fertility, and immune regulation.https://www.mdpi.com/2673-8430/4/1/2male reproductioncomplementcomplement regulatorstestisseminal plasmaprostate
spellingShingle Rachel L. Washburn
Complements from the Male Reproductive Tract: A Scoping Review
BioMed
male reproduction
complement
complement regulators
testis
seminal plasma
prostate
title Complements from the Male Reproductive Tract: A Scoping Review
title_full Complements from the Male Reproductive Tract: A Scoping Review
title_fullStr Complements from the Male Reproductive Tract: A Scoping Review
title_full_unstemmed Complements from the Male Reproductive Tract: A Scoping Review
title_short Complements from the Male Reproductive Tract: A Scoping Review
title_sort complements from the male reproductive tract a scoping review
topic male reproduction
complement
complement regulators
testis
seminal plasma
prostate
url https://www.mdpi.com/2673-8430/4/1/2
work_keys_str_mv AT rachellwashburn complementsfromthemalereproductivetractascopingreview