Complements from the Male Reproductive Tract: A Scoping Review
The organs of the male reproductive tract, including the testis, epididymis, prostate, seminal vesicles, and semen, must provide an immunoregulatory environment conducive to germ cell viability and successful fertilization. Many immune components, such as immune cells, have been investigated regardi...
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Format: | Article |
Language: | English |
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MDPI AG
2024-01-01
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Online Access: | https://www.mdpi.com/2673-8430/4/1/2 |
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author | Rachel L. Washburn |
author_facet | Rachel L. Washburn |
author_sort | Rachel L. Washburn |
collection | DOAJ |
description | The organs of the male reproductive tract, including the testis, epididymis, prostate, seminal vesicles, and semen, must provide an immunoregulatory environment conducive to germ cell viability and successful fertilization. Many immune components, such as immune cells, have been investigated regarding reproductive immunology and function; however, the investigation of the role of complement in this system has only more recently been gaining traction in research. This review focuses on complement in the male reproductive tract, with the goal of compiling information currently known about complement components detected in male reproductive organs and identifying areas in need of further research. Considering the recent and upcoming research about the noncanonical functions of complement, this information is relevant and applicable in the fields of reproductive immunology, fertility, and immune regulation. |
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format | Article |
id | doaj.art-e4b184b240a243b185599288ae0a9d42 |
institution | Directory Open Access Journal |
issn | 2673-8430 |
language | English |
last_indexed | 2024-04-24T18:32:48Z |
publishDate | 2024-01-01 |
publisher | MDPI AG |
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series | BioMed |
spelling | doaj.art-e4b184b240a243b185599288ae0a9d422024-03-27T13:22:24ZengMDPI AGBioMed2673-84302024-01-0141193810.3390/biomed4010002Complements from the Male Reproductive Tract: A Scoping ReviewRachel L. Washburn0Department of Life and Physical Sciences, School of Arts, Sciences and Education, Ivy Tech Community College, 8204 County Rd. 311, Sellersburg, IN 47172, USAThe organs of the male reproductive tract, including the testis, epididymis, prostate, seminal vesicles, and semen, must provide an immunoregulatory environment conducive to germ cell viability and successful fertilization. Many immune components, such as immune cells, have been investigated regarding reproductive immunology and function; however, the investigation of the role of complement in this system has only more recently been gaining traction in research. This review focuses on complement in the male reproductive tract, with the goal of compiling information currently known about complement components detected in male reproductive organs and identifying areas in need of further research. Considering the recent and upcoming research about the noncanonical functions of complement, this information is relevant and applicable in the fields of reproductive immunology, fertility, and immune regulation.https://www.mdpi.com/2673-8430/4/1/2male reproductioncomplementcomplement regulatorstestisseminal plasmaprostate |
spellingShingle | Rachel L. Washburn Complements from the Male Reproductive Tract: A Scoping Review BioMed male reproduction complement complement regulators testis seminal plasma prostate |
title | Complements from the Male Reproductive Tract: A Scoping Review |
title_full | Complements from the Male Reproductive Tract: A Scoping Review |
title_fullStr | Complements from the Male Reproductive Tract: A Scoping Review |
title_full_unstemmed | Complements from the Male Reproductive Tract: A Scoping Review |
title_short | Complements from the Male Reproductive Tract: A Scoping Review |
title_sort | complements from the male reproductive tract a scoping review |
topic | male reproduction complement complement regulators testis seminal plasma prostate |
url | https://www.mdpi.com/2673-8430/4/1/2 |
work_keys_str_mv | AT rachellwashburn complementsfromthemalereproductivetractascopingreview |