Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoines
<abstract language="eng">Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds. Some biological activities (antimicr...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2008-01-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000300029 |
| _version_ | 1818212749925154816 |
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| author | Silvânia Maria de Oliveira João Bosco Paraíso da Silva Marcelo Zaldini Hernandes Maria do Carmo Alves de Lima Suely Lins Galdino Ivan da Rocha Pitta |
| author_facet | Silvânia Maria de Oliveira João Bosco Paraíso da Silva Marcelo Zaldini Hernandes Maria do Carmo Alves de Lima Suely Lins Galdino Ivan da Rocha Pitta |
| author_sort | Silvânia Maria de Oliveira |
| collection | DOAJ |
| description | <abstract language="eng">Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds. Some biological activities (antimicrobial, anticonvulsant, schistosomicidal) are attributed to the chemical reactivity and consequent affinity of hydantoinic rings towards biomacromolecules. Therefore, knowledge about the chemistry of hydantoins has increased enormously. In this review, we present important aspects such as reactivity of hydantoins, acidity of hydantoins, spectroscopy and cristallographic properties, and biological activities of hydantoin and its derivatives. |
| first_indexed | 2024-12-12T05:53:21Z |
| format | Article |
| id | doaj.art-e4b185d889cf4a17bf72ad2b5b1dce80 |
| institution | Directory Open Access Journal |
| issn | 0100-4042 1678-7064 |
| language | English |
| last_indexed | 2024-12-12T05:53:21Z |
| publishDate | 2008-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-e4b185d889cf4a17bf72ad2b5b1dce802022-12-22T00:35:38ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642008-01-0131361462210.1590/S0100-40422008000300029Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoinesSilvânia Maria de OliveiraJoão Bosco Paraíso da SilvaMarcelo Zaldini HernandesMaria do Carmo Alves de LimaSuely Lins GaldinoIvan da Rocha Pitta<abstract language="eng">Hydantoin (imidazolidine-2,4-dione) is a 2,4-diketotetrahydroimidazole discovered by Baeyer in 1861. Thiohydantoins and derivatives were prepared, having chemical properties similar to the corresponding carbonyl compounds. Some biological activities (antimicrobial, anticonvulsant, schistosomicidal) are attributed to the chemical reactivity and consequent affinity of hydantoinic rings towards biomacromolecules. Therefore, knowledge about the chemistry of hydantoins has increased enormously. In this review, we present important aspects such as reactivity of hydantoins, acidity of hydantoins, spectroscopy and cristallographic properties, and biological activities of hydantoin and its derivatives.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000300029hydantoinreactivitybiological properties |
| spellingShingle | Silvânia Maria de Oliveira João Bosco Paraíso da Silva Marcelo Zaldini Hernandes Maria do Carmo Alves de Lima Suely Lins Galdino Ivan da Rocha Pitta Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoines Química Nova hydantoin reactivity biological properties |
| title | Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoines |
| title_full | Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoines |
| title_fullStr | Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoines |
| title_full_unstemmed | Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoines |
| title_short | Estrutura, reatividade e propriedades biológicas de hidantoínas Structure, reactivity, and biological properties of hidantoines |
| title_sort | estrutura reatividade e propriedades biologicas de hidantoinas structure reactivity and biological properties of hidantoines |
| topic | hydantoin reactivity biological properties |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000300029 |
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