Long-term peritoneal dialysate exposure modulates expression of membrane complement regulators in human peritoneal mesothelial cells

Long-term peritoneal dialysate exposure modulates expression of membrane complement regulators in human peritoneal mesothelial cells

The membrane complement regulators (CRegs) CD46, CD55, and CD59 are highly expressed on human peritoneal mesothelial cells. However, how mesothelial CRegs change according to the peritoneal dialysis (PD) history of patients has remained unclear. We therefore examined longitudinal changes in CRegs in...

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Bibliographic Details
Main Authors: Kazuma Kobayashi, Toshikazu Ozeki, Hangsoo Kim, Masaki Imai, Hiroshi Kojima, Daiki Iguchi, Sosuke Fukui, Masafumi Suzuki, Yasuhiro Suzuki, Shoichi Maruyama, Yasuhiko Ito, Masashi Mizuno
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Medicine
Subjects:
peritoneal dialysis
complement
complement regulator
peritoneal dialysate
mesothelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.972592/full

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