Single-cell transcriptome analysis reveals cellular heterogeneity in mouse intra- and extra articular ligaments

Single-cell transcriptome analysis reveals cellular heterogeneity in mouse intra- and extra articular ligaments

Cell heterogeneity in the mouse anterior cruciate ligament (ACL) and medial collateral ligament (MCL) is demonstrated using single-cell analysis with three types of fibroblasts identified, expressing Col14a1, Col12a1, or Col22a1.

Bibliographic Details
Main Authors:	Kyota Ishibashi, Kentaro Ikegami, Takashi Shimbo, Eiji Sasaki, Tomomi Kitayama, Yuzuru Nakamura, Takahiro Tsushima, Yasuyuki Ishibashi, Katsuto Tamai
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-11-01
Series:	Communications Biology
Online Access:	https://doi.org/10.1038/s42003-022-04196-w

Similar Items

Relationship between tunnel malposition and intra-articular degeneration in anterior cruciate ligament reconstruction
by: Daisuke Chiba, MD, et al.
Published: (2016-10-01)

Intra-articular Anterior Cruciate Ligament Reconstruction With Extra-articular Lateral Tenodesis of the Iliotibial Band
by: João Luiz Ellera Gomes, M.D., Ph.D., et al.
Published: (2017-10-01)

Comparison of the femoral tunnel enlargement after intra-articular versus extra-articular knee ligament reconstructive surgeries
by: Keisuke Kita, et al.
Published: (2017-07-01)

Surgical intra- and extra-articular anterior cruciate ligament reconstruction: a meta-analysis
by: Xiangyun Cheng, et al.
Published: (2020-06-01)

Greater medial proximal tibial slope is associated with bone marrow lesions in middle-aged women with early knee osteoarthritis
by: Hikaru K. Ishibashi, et al.
Published: (2023-11-01)

Failure load of the femoral insertion site of the anterior cruciate ligament in a porcine model: comparison of different portions and knee flexion angles
by: Shohei Yamauchi, et al.
Published: (2021-08-01)

Extra and Intra-articular Synovial Chondromatosis
by: Rajesh Kumar Chaudhary, et al.
Published: (2015-09-01)

Extra and Intra-articular Synovial Chondromatosis
by: Rajesh Kumar Chaudhary, et al.
Published: (2015-09-01)

Management of Extra-Articular and Intra-Articular Distal Radius Malunion
by: Ting-Yu Liu, et al.
Published: (2024-09-01)

An extra-osseous intra-articular osteochondroma of the elbow
by: Abdullah Nouri, MB, BCh, BAO (NUI, RCSI), et al.
Published: (2023-01-01)

Joint line convergence angle is the most associated alignment factor with the severity of medial knee osteoarthritis
by: Takahiro Tsushima, et al.
Published: (2024-07-01)

Longitudinal Single-Cell Transcriptomics Reveals a Role for Serpina3n-Mediated Resolution of Inflammation in a Mouse Colitis ModelSummary
by: Yen-Ting Ho, et al.
Published: (2021-01-01)

The Efficacy of Intra-Articular Versus Extra-Articular Corticosteroid Injections in the Thumb Carpometacarpal Joint
by: Brian M. Katt, MD, et al.
Published: (2022-05-01)

Combined Anterior Cruciate Ligament Reconstruction and Lateral Extra-Articular Tenodesis
by: David L. Bernholt, M.D., et al.
Published: (2019-08-01)

Mid‐term patient‐reported outcomes are inferior in opening‐wedge high tibial osteotomy patients with untreated medial meniscus posterior root tear
by: Eiji Sasaki, et al.
Published: (2024-10-01)

Reconstruction of the anterior cruciate ligament: comparison of analgesia using intrathecal morphine, intra-articular morphine and intra-articular levobupivacaine
by: Leandro Queiroz Pinheiro, et al.
Published: (2015-06-01)

Intra-articular administration of extra-virgin olive oil in degenerative osteoarthritis
by: Ahmet Pamiry, et al.
Published: (2024-06-01)

Effusion detected by ultrasonography and overweight may predict the risk of knee osteoarthritis in females with early knee osteoarthritis: a retrospective analysis of Iwaki cohort data
by: Kyota Ishibashi, et al.
Published: (2022-11-01)

Surgical indications for anterior cruciate ligament reconstruction combined with extra-articular lateral tenodesis or anterolateral ligament reconstruction
by: Diego Ariel de Lima, et al.

The use of silk fibroin coating to enhance intra-articular ligamentization of polyethylene terepthalate artificial ligament
by: Jia Jiang, et al.
Published: (2017-07-01)

Arthroscopic Management of Intra-articular Ligament Lesions on Distal Radius Fractures
by: Marcio Aurelio Aita, et al.
Published: (2021-05-01)

Influence of hamstring tendon and bone-patellar tendon-bone autografts on worsened patient reported outcome measurements in revision anterior cruciate ligament reconstruction: Comparing outcomes between primary and revision reconstructions
by: Eiji Sasaki, et al.
Published: (2022-07-01)

Double-Bundle Anterior Cruciate Ligament Repair and Augmentation With Lateral Extra-articular Tenodesis
by: Nguyen Quang Ton Quyen, M.D., et al.
Published: (2024-11-01)

NON-FREE GRAFTS IN ANTERIOR CRUCIATE LIGAMENT AND LATERAL EXTRA-ARTICULAR TENODESIS RECONSTRUCTION
by: V. V. Zayats
Published: (2020-05-01)

Arthroscopic-Assisted Lateral Meniscal Allograft Transplantation With Open Ligamentous Extra-Articular Tenodesis
by: Edward R. Floyd, M.S., et al.
Published: (2021-03-01)

Treatment of intra-articular hip malignancy with extra-articular resection, preservation of the acetabular columns, and total hip arthroplasty
by: Joel E. Wells, MD, MPH, et al.
Published: (2018-12-01)

Total Knee Arthroplasty with Extra- or Intra-Articular Correction Technique for Arthritic Knees with Extra-Articular Deformity of the Femur or Tibia: A Report of Three Cases
by: Piti Rattanaprichavej, et al.
Published: (2016-04-01)

Extra-articular resection of the hip joint for pelvic sarcomas: Are there any oncological and functional risks compared with intra-articular resection?
by: Tomohiro Fujiwara, et al.
Published: (2021-12-01)

Lateral extra-articular procedures in anterior cruciate ligament reconstruction: Narrative review on current evidence
by: Takeo Tokura, et al.
Published: (2025-03-01)

Extra-Articular Lateral Tenodesis for Anterior Cruciate Ligament Deficient Knee: A Case Report
by: Diego García-Germán, et al.
Published: (2013-01-01)

Anterior Cruciate Ligament Revision Using Quadriceps Tendon Autograft and Lateral Extra-Articular Tenodesis
by: Fabrizio Matassi, M.D., et al.
Published: (2025-01-01)

Anterior Cruciate Ligament Reconstruction Using Lateral Extra-Articular Procedures: A Systematic Review
by: Filippo Migliorini, et al.
Published: (2025-02-01)

Combined Anterior Cruciate Ligament Reconstruction and Lateral Extra-Articular Tenodesis: The “Over-the-Top” Technique
by: Stefano Zaffagnini MD, et al.
Published: (2023-09-01)

Lateral Extra-Articular Tenodesis Staple Risks Penetration of Anterior Cruciate Ligament Reconstruction Tunnel
by: Thomas E. Moran, M.D., et al.
Published: (2023-02-01)

The Effect of Arthroscopic Extra‐Articular Entire Coracohumeral Ligament Release for Patients with Recalcitrant Frozen Shoulder
by: Dan‐mei Li, et al.
Published: (2023-08-01)

Anatomic Double-Bundle ACL Reconstruction With Extra-articular Anterolateral Ligament Reconstruction and Internal Brace
by: Chih-Hao Chiu, M.D., Ph.D., et al.
Published: (2021-03-01)

Baker's cyst with extra‐ and intra‐articular synovial chondromatosis of knee: A case report
by: Sushant Kumar Khadka, et al.
Published: (2023-03-01)

Mobile bearing shows larger rollback motion than fixed bearing in total knee arthroplasty using a medial stabilising technique with a navigation system
by: Takahiro Tsushima, et al.
Published: (2024-07-01)

Incidence of anterior cruciate ligament injury patterns in Japanese judo players from a nationwide insurance database
by: Eiji Sasaki, et al.
Published: (2023-07-01)

Intra-Articular Cytokine Levels in Adolescent Patients after Anterior Cruciate Ligament Tear
by: Marco Bigoni, et al.
Published: (2018-01-01)