Novel nasal niosomes loaded with lacosamide and coated with chitosan: A possible pathway to target the brain to control partial-onset seizures
This work aimed to develop and produce lacosamide-loaded niosomes coated with chitosan (LCA-CTS-NSM) using a thin-film hydration method and the Box-Behnken design. The effect of three independent factors (Span 60 amount, chitosan concentration, and cholesterol amount) on vesicle size, entrapment eff...
Main Authors: | Alaa S. Tulbah, Mohammed H. Elkomy, Randa Mohammed Zaki, Hussein M. Eid, Essam M. Eissa, Adel A. Ali, Heba A. Yassin, Basmah Nasser Aldosari, Ibrahim A. Naguib, Amira H. Hassan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | International Journal of Pharmaceutics: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590156723000506 |
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