Cellulose Composites with Graphene for Tissue Engineering Applications
Tissue engineering is an interdisciplinary field that combines principles of engineering and life sciences to obtain biomaterials capable of maintaining, improving, or substituting the function of various tissues or even an entire organ. In virtue of its high availability, biocompatibility and versa...
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MDPI AG
2020-11-01
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Online Access: | https://www.mdpi.com/1996-1944/13/23/5347 |
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author | Madalina Oprea Stefan Ioan Voicu |
author_facet | Madalina Oprea Stefan Ioan Voicu |
author_sort | Madalina Oprea |
collection | DOAJ |
description | Tissue engineering is an interdisciplinary field that combines principles of engineering and life sciences to obtain biomaterials capable of maintaining, improving, or substituting the function of various tissues or even an entire organ. In virtue of its high availability, biocompatibility and versatility, cellulose was considered a promising platform for such applications. The combination of cellulose with graphene or graphene derivatives leads to the obtainment of superior composites in terms of cellular attachment, growth and proliferation, integration into host tissue, and stem cell differentiation toward specific lineages. The current review provides an up-to-date summary of the status of the field of cellulose composites with graphene for tissue engineering applications. The preparation methods and the biological performance of cellulose paper, bacterial cellulose, and cellulose derivatives-based composites with graphene, graphene oxide and reduced graphene oxide were mainly discussed. The importance of the cellulose-based matrix and the contribution of graphene and graphene derivatives fillers as well as several key applications of these hybrid materials, particularly for the development of multifunctional scaffolds for cell culture, bone and neural tissue regeneration were also highlighted. |
first_indexed | 2024-03-10T14:34:29Z |
format | Article |
id | doaj.art-e4bc319c3ea445ca8d5294e78995aa3d |
institution | Directory Open Access Journal |
issn | 1996-1944 |
language | English |
last_indexed | 2024-03-10T14:34:29Z |
publishDate | 2020-11-01 |
publisher | MDPI AG |
record_format | Article |
series | Materials |
spelling | doaj.art-e4bc319c3ea445ca8d5294e78995aa3d2023-11-20T22:20:19ZengMDPI AGMaterials1996-19442020-11-011323534710.3390/ma13235347Cellulose Composites with Graphene for Tissue Engineering ApplicationsMadalina Oprea0Stefan Ioan Voicu1Faculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, Gheorghe Polizu 1-7, 011061 Bucharest, RomaniaFaculty of Applied Chemistry and Materials Science, University Politehnica of Bucharest, Gheorghe Polizu 1-7, 011061 Bucharest, RomaniaTissue engineering is an interdisciplinary field that combines principles of engineering and life sciences to obtain biomaterials capable of maintaining, improving, or substituting the function of various tissues or even an entire organ. In virtue of its high availability, biocompatibility and versatility, cellulose was considered a promising platform for such applications. The combination of cellulose with graphene or graphene derivatives leads to the obtainment of superior composites in terms of cellular attachment, growth and proliferation, integration into host tissue, and stem cell differentiation toward specific lineages. The current review provides an up-to-date summary of the status of the field of cellulose composites with graphene for tissue engineering applications. The preparation methods and the biological performance of cellulose paper, bacterial cellulose, and cellulose derivatives-based composites with graphene, graphene oxide and reduced graphene oxide were mainly discussed. The importance of the cellulose-based matrix and the contribution of graphene and graphene derivatives fillers as well as several key applications of these hybrid materials, particularly for the development of multifunctional scaffolds for cell culture, bone and neural tissue regeneration were also highlighted.https://www.mdpi.com/1996-1944/13/23/5347scaffoldsmembraneshydrogelscellulosetissue engineering |
spellingShingle | Madalina Oprea Stefan Ioan Voicu Cellulose Composites with Graphene for Tissue Engineering Applications Materials scaffolds membranes hydrogels cellulose tissue engineering |
title | Cellulose Composites with Graphene for Tissue Engineering Applications |
title_full | Cellulose Composites with Graphene for Tissue Engineering Applications |
title_fullStr | Cellulose Composites with Graphene for Tissue Engineering Applications |
title_full_unstemmed | Cellulose Composites with Graphene for Tissue Engineering Applications |
title_short | Cellulose Composites with Graphene for Tissue Engineering Applications |
title_sort | cellulose composites with graphene for tissue engineering applications |
topic | scaffolds membranes hydrogels cellulose tissue engineering |
url | https://www.mdpi.com/1996-1944/13/23/5347 |
work_keys_str_mv | AT madalinaoprea cellulosecompositeswithgraphenefortissueengineeringapplications AT stefanioanvoicu cellulosecompositeswithgraphenefortissueengineeringapplications |