Platelet-rich plasma inhibits Adriamycin-induced inflammation via blocking the NF-κB pathway in articular chondrocytes

Platelet-rich plasma inhibits Adriamycin-induced inflammation via blocking the NF-κB pathway in articular chondrocytes

Abstract Background Previous studies showed that doxorubicin could lead to osteoarthritis (OA) by inducing chondrocyte inflammation and apoptosis. Besides, it is reported that platelet-rich plasma (PRP) could suppress the activation of inflammatory NF-κB signaling. Here, we aimed to determine whethe...

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Bibliographic Details
Main Authors: Haijun Zhao, Weijie Zhu, Wude Mao, Chengkai Shen
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Molecular Medicine
Subjects:
PRP
Doxorubicin
Osteoarthritis
Chondrocyte
Inflammation
NF-κb
Online Access:https://doi.org/10.1186/s10020-021-00314-2

Internet

https://doi.org/10.1186/s10020-021-00314-2

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