Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET): protocol for an effectiveness-implementation study of a structured model of care for psychosis in youth and emerging adults
Introduction While early psychosis intervention (EPI) has proliferated in recent years amid evidence of its effectiveness, programmes often struggle to deliver consistent, recovery-based care. NAVIGATE is a manualised model of EPI with demonstrated effectiveness consisting of four components: indivi...
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| Format: | Article |
| Language: | English |
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BMJ Publishing Group
2020-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/10/6/e034280.full |
| _version_ | 1831669768991539200 |
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| author | Sophie Soklaridis Paul Kurdyak Claire de Oliveira Simone Dahrouge Joanna Henderson Aristotle N Voineskos Kelly K Anderson Nicole Kozloff George Foussias Janet Durbin Sanjeev Sockalingam Jean Addington Donald Addington Augustina Ampofo Melanie Barwick Sarah Bromley Jasmyn E A Cunningham Lillian Duda Catherine Ford Sheila Gallagher John D Haltigan Alexia Jaouich Dielle Miranda Patrick Mitchell Josette Morin Valerie Primeau Eva Serhal Diana Urajnik Krista Whittard Juveria Zaheer |
| author_facet | Sophie Soklaridis Paul Kurdyak Claire de Oliveira Simone Dahrouge Joanna Henderson Aristotle N Voineskos Kelly K Anderson Nicole Kozloff George Foussias Janet Durbin Sanjeev Sockalingam Jean Addington Donald Addington Augustina Ampofo Melanie Barwick Sarah Bromley Jasmyn E A Cunningham Lillian Duda Catherine Ford Sheila Gallagher John D Haltigan Alexia Jaouich Dielle Miranda Patrick Mitchell Josette Morin Valerie Primeau Eva Serhal Diana Urajnik Krista Whittard Juveria Zaheer |
| author_sort | Sophie Soklaridis |
| collection | DOAJ |
| description | Introduction While early psychosis intervention (EPI) has proliferated in recent years amid evidence of its effectiveness, programmes often struggle to deliver consistent, recovery-based care. NAVIGATE is a manualised model of EPI with demonstrated effectiveness consisting of four components: individualised medication management, individual resiliency training, supported employment and education and family education. We aim to implement NAVIGATE in geographically diverse EPI programmes in Ontario, Canada, evaluating implementation and its effect on fidelity to the EPI model, as well as individual-level outcomes (patient/family member-reported and interviewer-rated), system-level outcomes (captured in provincial administrative databases) and engagement of participants with lived experience.Methods and analysis This is a multisite, non-randomised pragmatic hybrid effectiveness-implementation type III mixed methods study coordinated at the Centre for Addiction and Mental Health (CAMH) in Toronto. Implementation is supported by the Provincial System Support Program, a CAMH-based programme with provincial offices across Ontario, and Extension of Community Healthcare Outcomes Ontario Mental Health at CAMH and the University of Toronto. The primary outcome is fidelity to the EPI model as measured using the First Episode Psychosis Services—Fidelity Scale. Four hundred participants in the EPI programmes will be recruited and followed using both individual-level assessments and health administrative data for 2 years following NAVIGATE initiation. People with lived experience will be engaged in all aspects of the project, including through youth and family advisory committees.Ethics and dissemination Research ethics board approval has been obtained from CAMH and institutions overseeing the local EPI programmes. Study findings will be reported in scientific journal articles and shared with key stakeholders including youth, family members, programme staff and policymakers.Trial registration number NCT03919760; Pre-results. |
| first_indexed | 2024-12-19T23:05:35Z |
| format | Article |
| id | doaj.art-e4c36748f33b4a378501f3fac71b4721 |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-12-19T23:05:35Z |
| publishDate | 2020-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-e4c36748f33b4a378501f3fac71b47212022-12-21T20:02:23ZengBMJ Publishing GroupBMJ Open2044-60552020-06-0110610.1136/bmjopen-2019-034280Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET): protocol for an effectiveness-implementation study of a structured model of care for psychosis in youth and emerging adultsSophie Soklaridis0Paul Kurdyak1Claire de Oliveira2Simone Dahrouge3Joanna Henderson4Aristotle N Voineskos5Kelly K Anderson6Nicole Kozloff7George Foussias8Janet Durbin9Sanjeev Sockalingam10Jean Addington11Donald Addington12Augustina Ampofo13Melanie Barwick14Sarah Bromley15Jasmyn E A Cunningham16Lillian Duda17Catherine Ford18Sheila Gallagher19John D Haltigan20Alexia Jaouich21Dielle Miranda22Patrick Mitchell23Josette Morin24Valerie Primeau25Eva Serhal26Diana Urajnik27Krista Whittard28Juveria Zaheer29The Centre for Addiction and Mental Health, Toronto, Ontario, CanadaPsychiatry, University of Toronto, Toronto, Ontario, CanadaInstitute for Mental Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada7 C.T. Lamont Primary Health Care Research Centre, Elisabeth Bruyère Research Institute, Ottawa, Ontario, CanadaPsychiatry, University of Toronto, Toronto, Ontario, CanadaSlaight Family Centre for Youth in Transition, Centre for Addiction and Mental Health, Toronto, Ontario, CanadaEpidemiology & Biostatistics, Western University, London, Ontario, CanadaSlaight Family Centre for Youth in Transition, Centre for Addiction and Mental Health, Toronto, Ontario, CanadaSlaight Family Centre for Youth in Transition, Centre for Addiction and Mental Health, Toronto, Ontario, CanadaDepartment of Psychiatry, University of Toronto, Toronto, Ontario, CanadaDepartment of Psychiatry, University of Toronto, Toronto, Ontario, CanadaDepartment of Psychiatry, University of Calgary, Calgary, Alberta, CanadaDepartment of Psychiatry, University of Calgary, Calgary, Alberta, CanadaCentre for Addiction and Mental Health, Toronto, Ontario, CanadaDepartment of Psychiatry, University of Toronto, Toronto, Ontario, CanadaSlaight Family Centre for Youth in Transition, Centre for Addiction and Mental Health, Toronto, Ontario, CanadaSlaight Family Centre for Youth in Transition, Centre for Addiction and Mental Health, Toronto, Ontario, CanadaCentre for Addiction and Mental Health, Toronto, Ontario, CanadaOntario Ministry of Health, Toronto, Ontario, CanadaDurham Amaze Early Psychosis Intervention Program, Lakeridge Health, Whitby, Ontario, CanadaDepartment of Psychiatry, University of Toronto, Toronto, Ontario, CanadaProvincial System Support Program, Centre for Addiction and Mental Health, Toronto, Ontario, CanadaSlaight Family Centre for Youth in Transition, Centre for Addiction and Mental Health, Toronto, Ontario, CanadaOntario Ministry of Health, Toronto, Ontario, CanadaRegional Early Intervention in Psychosis Service, North Bay Regional Health Centre, North Bay, Ontario, CanadaRegional Early Intervention in Psychosis Service, North Bay Regional Health Centre, North Bay, Ontario, CanadaInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, CanadaHuman Sciences, Social and Population Health, Northern Ontario School of Medicine, Sudbury, Ontario, CanadaEarly Psychosis Intervention, Niagara Region Public Health, Thorold, Ontario, CanadaDepartment of Psychiatry, University of Toronto, Toronto, Ontario, CanadaIntroduction While early psychosis intervention (EPI) has proliferated in recent years amid evidence of its effectiveness, programmes often struggle to deliver consistent, recovery-based care. NAVIGATE is a manualised model of EPI with demonstrated effectiveness consisting of four components: individualised medication management, individual resiliency training, supported employment and education and family education. We aim to implement NAVIGATE in geographically diverse EPI programmes in Ontario, Canada, evaluating implementation and its effect on fidelity to the EPI model, as well as individual-level outcomes (patient/family member-reported and interviewer-rated), system-level outcomes (captured in provincial administrative databases) and engagement of participants with lived experience.Methods and analysis This is a multisite, non-randomised pragmatic hybrid effectiveness-implementation type III mixed methods study coordinated at the Centre for Addiction and Mental Health (CAMH) in Toronto. Implementation is supported by the Provincial System Support Program, a CAMH-based programme with provincial offices across Ontario, and Extension of Community Healthcare Outcomes Ontario Mental Health at CAMH and the University of Toronto. The primary outcome is fidelity to the EPI model as measured using the First Episode Psychosis Services—Fidelity Scale. Four hundred participants in the EPI programmes will be recruited and followed using both individual-level assessments and health administrative data for 2 years following NAVIGATE initiation. People with lived experience will be engaged in all aspects of the project, including through youth and family advisory committees.Ethics and dissemination Research ethics board approval has been obtained from CAMH and institutions overseeing the local EPI programmes. Study findings will be reported in scientific journal articles and shared with key stakeholders including youth, family members, programme staff and policymakers.Trial registration number NCT03919760; Pre-results.https://bmjopen.bmj.com/content/10/6/e034280.full |
| spellingShingle | Sophie Soklaridis Paul Kurdyak Claire de Oliveira Simone Dahrouge Joanna Henderson Aristotle N Voineskos Kelly K Anderson Nicole Kozloff George Foussias Janet Durbin Sanjeev Sockalingam Jean Addington Donald Addington Augustina Ampofo Melanie Barwick Sarah Bromley Jasmyn E A Cunningham Lillian Duda Catherine Ford Sheila Gallagher John D Haltigan Alexia Jaouich Dielle Miranda Patrick Mitchell Josette Morin Valerie Primeau Eva Serhal Diana Urajnik Krista Whittard Juveria Zaheer Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET): protocol for an effectiveness-implementation study of a structured model of care for psychosis in youth and emerging adults BMJ Open |
| title | Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET): protocol for an effectiveness-implementation study of a structured model of care for psychosis in youth and emerging adults |
| title_full | Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET): protocol for an effectiveness-implementation study of a structured model of care for psychosis in youth and emerging adults |
| title_fullStr | Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET): protocol for an effectiveness-implementation study of a structured model of care for psychosis in youth and emerging adults |
| title_full_unstemmed | Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET): protocol for an effectiveness-implementation study of a structured model of care for psychosis in youth and emerging adults |
| title_short | Early Psychosis Intervention-Spreading Evidence-based Treatment (EPI-SET): protocol for an effectiveness-implementation study of a structured model of care for psychosis in youth and emerging adults |
| title_sort | early psychosis intervention spreading evidence based treatment epi set protocol for an effectiveness implementation study of a structured model of care for psychosis in youth and emerging adults |
| url | https://bmjopen.bmj.com/content/10/6/e034280.full |
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