Axl receptor tyrosine kinase is a regulator of apolipoprotein E

Axl receptor tyrosine kinase is a regulator of apolipoprotein E

Abstract Alzheimer’s disease (AD), the leading cause of dementia, is a chronic neurodegenerative disease. Apolipoprotein E (apoE), which carries lipids in the brain in the form of lipoproteins, plays an undisputed role in AD pathophysiology. A high-throughput phenotypic screen was conducted using a...

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Bibliographic Details
Main Authors: Wenchen Zhao, Jianjia Fan, Iva Kulic, Cheryl Koh, Amanda Clark, Johan Meuller, Ola Engkvist, Samantha Barichievy, Carina Raynoschek, Ryan Hicks, Marcello Maresca, Qi Wang, Dean G. Brown, Alvin Lok, Cameron Parro, Jerome Robert, Hsien-Ya Chou, Andrea M. Zuhl, Michael W. Wood, Nicholas J. Brandon, Cheryl L. Wellington
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Brain
Subjects:
Apolipoprotein E
AXL
Astrocyte
Alzheimer’s disease
Online Access:http://link.springer.com/article/10.1186/s13041-020-00609-1

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