Individual prediction of hemispheric similarity of functional connectivity during normal aging
In the aging process of normal people, the functional activity pattern of brain is in constant change, and the change of brain runs through the whole life cycle, which plays a crucial role in the track of individual development. In recent years, some studies had been carried out on the brain functio...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Psychiatry |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1016807/full |
| _version_ | 1798029545299771392 |
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| author | Yingteng Zhang |
| author_facet | Yingteng Zhang |
| author_sort | Yingteng Zhang |
| collection | DOAJ |
| description | In the aging process of normal people, the functional activity pattern of brain is in constant change, and the change of brain runs through the whole life cycle, which plays a crucial role in the track of individual development. In recent years, some studies had been carried out on the brain functional activity pattern during individual aging process from different perspectives, which provided an opportunity for the problem we want to study. In this study, we used the resting-state functional magnetic resonance imaging (rs-fMRI) data from Cambridge Center for Aging and Neuroscience (Cam-CAN) database with large sample and long lifespan, and computed the functional connectivity (FC) values for each individual. Based on these values, the hemispheric similarity of functional connectivity (HSFC) obtained by Pearson correlation was used as the starting point of this study. We evaluated the ability of individual recognition of HSFC in the process of aging, as well as the variation trend with aging process. The results showed that HSFC could be used to identify individuals effectively, and it could reflect the change rule in the process of aging. In addition, we observed a series of results at the sub-module level and find that the recognition rate in the sub-module was different from each other, as well as the trend with age. Finally, as a validation, we repeated the main results by human brainnetome atlas (BNA) template and without global signal regression, found that had a good robustness. This also provides a new clue to hemispherical change patterns during normal aging. |
| first_indexed | 2024-04-11T19:25:51Z |
| format | Article |
| id | doaj.art-e4c64a4e33bd49db8dbb0d1054b4c532 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-11T19:25:51Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-e4c64a4e33bd49db8dbb0d1054b4c5322022-12-22T04:07:09ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-09-011310.3389/fpsyt.2022.10168071016807Individual prediction of hemispheric similarity of functional connectivity during normal agingYingteng ZhangIn the aging process of normal people, the functional activity pattern of brain is in constant change, and the change of brain runs through the whole life cycle, which plays a crucial role in the track of individual development. In recent years, some studies had been carried out on the brain functional activity pattern during individual aging process from different perspectives, which provided an opportunity for the problem we want to study. In this study, we used the resting-state functional magnetic resonance imaging (rs-fMRI) data from Cambridge Center for Aging and Neuroscience (Cam-CAN) database with large sample and long lifespan, and computed the functional connectivity (FC) values for each individual. Based on these values, the hemispheric similarity of functional connectivity (HSFC) obtained by Pearson correlation was used as the starting point of this study. We evaluated the ability of individual recognition of HSFC in the process of aging, as well as the variation trend with aging process. The results showed that HSFC could be used to identify individuals effectively, and it could reflect the change rule in the process of aging. In addition, we observed a series of results at the sub-module level and find that the recognition rate in the sub-module was different from each other, as well as the trend with age. Finally, as a validation, we repeated the main results by human brainnetome atlas (BNA) template and without global signal regression, found that had a good robustness. This also provides a new clue to hemispherical change patterns during normal aging.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1016807/fullhemispheric similarity of functional connectivityfunctional MRInormal agingindividual recognitionglobal signal |
| spellingShingle | Yingteng Zhang Individual prediction of hemispheric similarity of functional connectivity during normal aging Frontiers in Psychiatry hemispheric similarity of functional connectivity functional MRI normal aging individual recognition global signal |
| title | Individual prediction of hemispheric similarity of functional connectivity during normal aging |
| title_full | Individual prediction of hemispheric similarity of functional connectivity during normal aging |
| title_fullStr | Individual prediction of hemispheric similarity of functional connectivity during normal aging |
| title_full_unstemmed | Individual prediction of hemispheric similarity of functional connectivity during normal aging |
| title_short | Individual prediction of hemispheric similarity of functional connectivity during normal aging |
| title_sort | individual prediction of hemispheric similarity of functional connectivity during normal aging |
| topic | hemispheric similarity of functional connectivity functional MRI normal aging individual recognition global signal |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.1016807/full |
| work_keys_str_mv | AT yingtengzhang individualpredictionofhemisphericsimilarityoffunctionalconnectivityduringnormalaging |