Questions on Mediterranean Spotted Fever a Century after Its Discovery
Mediterranean spotted fever (MSF) was first described in 1910. Twenty years later, it was recognized as a rickettsial disease transmitted by the brown dog tick. In contrast to Rocky Mountain spotted fever (RMSF), MSF was thought to be a benign disease; however, the first severe case that resulted in...
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2008-09-01
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| Series: | Emerging Infectious Diseases |
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| Online Access: | https://wwwnc.cdc.gov/eid/article/14/9/07-1133_article |
| _version_ | 1819261675329552384 |
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| author | Clarisse Rovery Philippe Brouqui Didier Raoult |
| author_facet | Clarisse Rovery Philippe Brouqui Didier Raoult |
| author_sort | Clarisse Rovery |
| collection | DOAJ |
| description | Mediterranean spotted fever (MSF) was first described in 1910. Twenty years later, it was recognized as a rickettsial disease transmitted by the brown dog tick. In contrast to Rocky Mountain spotted fever (RMSF), MSF was thought to be a benign disease; however, the first severe case that resulted in death was reported in France in the 1980s. We have noted important changes in the epidemiology of MSF in the last 10 years, with emergence and reemergence of MSF in several countries. Advanced molecular tools have allowed Rickettsia conorii conorii to be classified as a subspecies of R. conorii. New clinical features, such as multiple eschars, have been recently reported. Moreover, MSF has become more severe than RMSF; the mortality rate was as high as 32% in Portugal in 1997. Whether Rhipicephalus sanguineus is the only vector and reservoir for R. conorii conorii is a question not yet answered. |
| first_indexed | 2024-12-23T19:45:34Z |
| format | Article |
| id | doaj.art-e4d0c9b59ae14f57a311124e4e61a1a1 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-23T19:45:34Z |
| publishDate | 2008-09-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-e4d0c9b59ae14f57a311124e4e61a1a12022-12-21T17:33:32ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592008-09-011491360136710.3201/eid1409.071133Questions on Mediterranean Spotted Fever a Century after Its DiscoveryClarisse RoveryPhilippe BrouquiDidier RaoultMediterranean spotted fever (MSF) was first described in 1910. Twenty years later, it was recognized as a rickettsial disease transmitted by the brown dog tick. In contrast to Rocky Mountain spotted fever (RMSF), MSF was thought to be a benign disease; however, the first severe case that resulted in death was reported in France in the 1980s. We have noted important changes in the epidemiology of MSF in the last 10 years, with emergence and reemergence of MSF in several countries. Advanced molecular tools have allowed Rickettsia conorii conorii to be classified as a subspecies of R. conorii. New clinical features, such as multiple eschars, have been recently reported. Moreover, MSF has become more severe than RMSF; the mortality rate was as high as 32% in Portugal in 1997. Whether Rhipicephalus sanguineus is the only vector and reservoir for R. conorii conorii is a question not yet answered.https://wwwnc.cdc.gov/eid/article/14/9/07-1133_articleMediterranean spotted feverRickettsia conoriisynopsis |
| spellingShingle | Clarisse Rovery Philippe Brouqui Didier Raoult Questions on Mediterranean Spotted Fever a Century after Its Discovery Emerging Infectious Diseases Mediterranean spotted fever Rickettsia conorii synopsis |
| title | Questions on Mediterranean Spotted Fever a Century after Its Discovery |
| title_full | Questions on Mediterranean Spotted Fever a Century after Its Discovery |
| title_fullStr | Questions on Mediterranean Spotted Fever a Century after Its Discovery |
| title_full_unstemmed | Questions on Mediterranean Spotted Fever a Century after Its Discovery |
| title_short | Questions on Mediterranean Spotted Fever a Century after Its Discovery |
| title_sort | questions on mediterranean spotted fever a century after its discovery |
| topic | Mediterranean spotted fever Rickettsia conorii synopsis |
| url | https://wwwnc.cdc.gov/eid/article/14/9/07-1133_article |
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