HLA-Clus: HLA class I clustering based on 3D structure

HLA-Clus: HLA class I clustering based on 3D structure

Abstract Background In a previous paper, we classified populated HLA class I alleles into supertypes and subtypes based on the similarity of 3D landscape of peptide binding grooves, using newly defined structure distance metric and hierarchical clustering approach. Compared to other approaches, our...

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Bibliographic Details
Main Authors: Yue Shen, Jerry M. Parks, Jeremy C. Smith
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Bioinformatics
Subjects:
Human leukocyte antigen
Protein structure
Clustering
Machine learning
Online Access:https://doi.org/10.1186/s12859-023-05297-x

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