Role of CD133 in human embryonic stem cell proliferation and teratoma formation

Role of CD133 in human embryonic stem cell proliferation and teratoma formation

Abstract Background Pluripotent stem cells (PSCs), including human embryonic stem cells (hESCs), hold great potential for regenerative medicine and cell therapy. One of the major hurdles hindering the clinical development of PSC-based therapy is the potential risk of tumorigenesis. CD133 (Prominin 1...

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Bibliographic Details
Main Authors: Hua Wang, Peng Gong, Jie Li, Yudong Fu, Zhongcheng Zhou, Lin Liu
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Stem Cell Research & Therapy
Subjects:
CD133
Human embryonic stem cell
Teratoma
Online Access:http://link.springer.com/article/10.1186/s13287-020-01729-0

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