Diagnostic value of dual-energy CT and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extension
ObjectiveTo describe the clinicopathological and imaging features of mixed endometrial stromal and smooth muscle tumors with intracardiac extension and to explore the diagnostic value of dual-energy computed tomography (DECT) for this rare entity.Materials and methodsThis retrospective study analyze...
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.917399/full |
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| author | Yi-yang Liu Yi-yang Liu Zhan Yu Rui Wang Rui Wang Kui-sheng Chen Song-wei Yue Jun Li Xue-mei Gao Chang-mao Ding Zi-xin Wu Xi Zhao Jian-bo Gao Jian-bo Gao |
| author_facet | Yi-yang Liu Yi-yang Liu Zhan Yu Rui Wang Rui Wang Kui-sheng Chen Song-wei Yue Jun Li Xue-mei Gao Chang-mao Ding Zi-xin Wu Xi Zhao Jian-bo Gao Jian-bo Gao |
| author_sort | Yi-yang Liu |
| collection | DOAJ |
| description | ObjectiveTo describe the clinicopathological and imaging features of mixed endometrial stromal and smooth muscle tumors with intracardiac extension and to explore the diagnostic value of dual-energy computed tomography (DECT) for this rare entity.Materials and methodsThis retrospective study analyzed the clinicopathological data and images of a 41-year-old female patient with pathologically documented mixed endometrial stromal and smooth muscle tumors with intracardiac extension who had undergone DECT examination. Seven virtual monoenergetic images (VMIs) in 10-kiloelectron volt (keV) intervals (range = 40–100 keV), iodine density (ID) maps, and Z effective (Zeff) maps were reconstructed, and lesion conspicuity was assessed. Tumor homology was analyzed using quantitative DECT parameters and energy spectrum attenuation curve.ResultsThe patient complained of a 10-day history of bilateral lower extremity edema. Computed tomography showed a hypoattenuating filling defect located within the paracervical vein that extended into the right atrium to the ventricle through the right iliac veins and inferior vena cava (IVC). Intracardiac and intravenous lesions mainly demonstrated moderate progressive enhancement, with localized non-enhancing necrotic areas on contrast-enhanced CT. Multiple nodules showing progressive enhancement (long-T1 signal, long-T2 signal) were observed at the fundus of the uterus on dynamic contrast-enhanced magnetic resonance imaging (MRI), which were deemed the primary lesions of the tumor. Overall, the tumor was characterized by a small primary lesion with extensive vascular extension. In addition, the 40 keV VMIs reconstructions were found to provide best visualization for the early detection of tumors.ConclusionAlthough a definitive diagnosis of MESSMT with intracardiac extension requires confirmation by histopathological examination, imaging examination can be used to characterize the extent of the lesion. The dual-energy dataset facilitates tumor visualization and homology evaluation. |
| first_indexed | 2024-04-11T20:35:35Z |
| format | Article |
| id | doaj.art-e4d3e7e26e284d839b016353e6d1dac1 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-11T20:35:35Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-e4d3e7e26e284d839b016353e6d1dac12022-12-22T04:04:23ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-09-01910.3389/fcvm.2022.917399917399Diagnostic value of dual-energy CT and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extensionYi-yang Liu0Yi-yang Liu1Zhan Yu2Rui Wang3Rui Wang4Kui-sheng Chen5Song-wei Yue6Jun Li7Xue-mei Gao8Chang-mao Ding9Zi-xin Wu10Xi Zhao11Jian-bo Gao12Jian-bo Gao13Department of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Key Laboratory of Imaging Diagnosis and Treatment for Digestive System Tumor, Zhengzhou, ChinaDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Key Laboratory of Imaging Diagnosis and Treatment for Digestive System Tumor, Zhengzhou, ChinaDepartment of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Magnetic Resonance, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Urology Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Customer Services, Siemens Healthineers, Shanghai, ChinaDepartment of Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Key Laboratory of Imaging Diagnosis and Treatment for Digestive System Tumor, Zhengzhou, ChinaObjectiveTo describe the clinicopathological and imaging features of mixed endometrial stromal and smooth muscle tumors with intracardiac extension and to explore the diagnostic value of dual-energy computed tomography (DECT) for this rare entity.Materials and methodsThis retrospective study analyzed the clinicopathological data and images of a 41-year-old female patient with pathologically documented mixed endometrial stromal and smooth muscle tumors with intracardiac extension who had undergone DECT examination. Seven virtual monoenergetic images (VMIs) in 10-kiloelectron volt (keV) intervals (range = 40–100 keV), iodine density (ID) maps, and Z effective (Zeff) maps were reconstructed, and lesion conspicuity was assessed. Tumor homology was analyzed using quantitative DECT parameters and energy spectrum attenuation curve.ResultsThe patient complained of a 10-day history of bilateral lower extremity edema. Computed tomography showed a hypoattenuating filling defect located within the paracervical vein that extended into the right atrium to the ventricle through the right iliac veins and inferior vena cava (IVC). Intracardiac and intravenous lesions mainly demonstrated moderate progressive enhancement, with localized non-enhancing necrotic areas on contrast-enhanced CT. Multiple nodules showing progressive enhancement (long-T1 signal, long-T2 signal) were observed at the fundus of the uterus on dynamic contrast-enhanced magnetic resonance imaging (MRI), which were deemed the primary lesions of the tumor. Overall, the tumor was characterized by a small primary lesion with extensive vascular extension. In addition, the 40 keV VMIs reconstructions were found to provide best visualization for the early detection of tumors.ConclusionAlthough a definitive diagnosis of MESSMT with intracardiac extension requires confirmation by histopathological examination, imaging examination can be used to characterize the extent of the lesion. The dual-energy dataset facilitates tumor visualization and homology evaluation.https://www.frontiersin.org/articles/10.3389/fcvm.2022.917399/fullintracardiac extensionMESSMTintravascular extensiondual-energy CTdiagnosis |
| spellingShingle | Yi-yang Liu Yi-yang Liu Zhan Yu Rui Wang Rui Wang Kui-sheng Chen Song-wei Yue Jun Li Xue-mei Gao Chang-mao Ding Zi-xin Wu Xi Zhao Jian-bo Gao Jian-bo Gao Diagnostic value of dual-energy CT and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extension Frontiers in Cardiovascular Medicine intracardiac extension MESSMT intravascular extension dual-energy CT diagnosis |
| title | Diagnostic value of dual-energy CT and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extension |
| title_full | Diagnostic value of dual-energy CT and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extension |
| title_fullStr | Diagnostic value of dual-energy CT and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extension |
| title_full_unstemmed | Diagnostic value of dual-energy CT and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extension |
| title_short | Diagnostic value of dual-energy CT and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extension |
| title_sort | diagnostic value of dual energy ct and clinicopathological and imaging feature analysis of mixed endometrial stromal and smooth muscle tumors with intracardiac extension |
| topic | intracardiac extension MESSMT intravascular extension dual-energy CT diagnosis |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.917399/full |
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