Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis
Objective We reviewed the association between hypertensive disorders of pregnancy (HDP) and the risk of attention-deficit/hyperactivity disorder (ADHD) in children. Methods We searched the databases of PubMed, Embase, ScienceDirect, CENTRAL, and Google Scholar for studies. Results Twelve studies wer...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-10-01
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| Series: | Hypertension in Pregnancy |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/10641955.2022.2079674 |
| _version_ | 1797681551563030528 |
|---|---|
| author | Jiejing Zhao Lihua Xia |
| author_facet | Jiejing Zhao Lihua Xia |
| author_sort | Jiejing Zhao |
| collection | DOAJ |
| description | Objective We reviewed the association between hypertensive disorders of pregnancy (HDP) and the risk of attention-deficit/hyperactivity disorder (ADHD) in children. Methods We searched the databases of PubMed, Embase, ScienceDirect, CENTRAL, and Google Scholar for studies. Results Twelve studies were included. Meta-analysis demonstrated that history of HDP results in a statistically significant increased risk of ADHD. Subgroup analysis of cohort and case-control studies also yielded similar results. Pre-eclampsia and chronic hypertension were associated with a statistically significant increased risk of ADHD in the offspring but not pregnancy-induced hypertension. Conclusion Exposure to HDP significantly increases the risk of ADHD in the offspring. |
| first_indexed | 2024-03-11T23:46:30Z |
| format | Article |
| id | doaj.art-e4d44ab771894e418d71afc3766a8599 |
| institution | Directory Open Access Journal |
| issn | 1064-1955 1525-6065 |
| language | English |
| last_indexed | 2024-03-11T23:46:30Z |
| publishDate | 2022-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj.art-e4d44ab771894e418d71afc3766a85992023-09-19T09:24:44ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652022-10-01413-414915810.1080/10641955.2022.20796742079674Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysisJiejing Zhao0Lihua Xia1Huzhou Maternity & Child Health Care HospitalHuzhou Maternity & Child Health Care HospitalObjective We reviewed the association between hypertensive disorders of pregnancy (HDP) and the risk of attention-deficit/hyperactivity disorder (ADHD) in children. Methods We searched the databases of PubMed, Embase, ScienceDirect, CENTRAL, and Google Scholar for studies. Results Twelve studies were included. Meta-analysis demonstrated that history of HDP results in a statistically significant increased risk of ADHD. Subgroup analysis of cohort and case-control studies also yielded similar results. Pre-eclampsia and chronic hypertension were associated with a statistically significant increased risk of ADHD in the offspring but not pregnancy-induced hypertension. Conclusion Exposure to HDP significantly increases the risk of ADHD in the offspring.http://dx.doi.org/10.1080/10641955.2022.2079674neurodevelopmental disordershypertensionpre-eclampsiagestational hypertensionadhd |
| spellingShingle | Jiejing Zhao Lihua Xia Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis Hypertension in Pregnancy neurodevelopmental disorders hypertension pre-eclampsia gestational hypertension adhd |
| title | Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis |
| title_full | Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis |
| title_fullStr | Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis |
| title_full_unstemmed | Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis |
| title_short | Association between hypertensive disorders of pregnancy and risk of attention-deficit/hyperactivity disorder in the offspring: a systematic review and meta-analysis |
| title_sort | association between hypertensive disorders of pregnancy and risk of attention deficit hyperactivity disorder in the offspring a systematic review and meta analysis |
| topic | neurodevelopmental disorders hypertension pre-eclampsia gestational hypertension adhd |
| url | http://dx.doi.org/10.1080/10641955.2022.2079674 |
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