Aβ Beyond the AD Pathology: Exploring the Structural Response of Membranes Exposed to Nascent Aβ Peptide
The physiological and pathological roles of nascent amyloid beta (Aβ) monomers are still debated in the literature. Their involvement in the pathological route of Alzheimer’s Disease (AD) is currently considered to be the most relevant, triggered by their aggregation into structured oligomers, a tox...
Main Authors: | Valeria Rondelli, Mario Salmona, Laura Colombo, Giovanna Fragneto, Giulia C. Fadda, Laura Cantu’, Elena Del Favero |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/21/8295 |
Similar Items
-
AmyP53 Prevents the Formation of Neurotoxic β-Amyloid Oligomers through an Unprecedent Mechanism of Interaction with Gangliosides: Insights for Alzheimer’s Disease Therapy
by: Fodil Azzaz, et al.
Published: (2023-01-01) -
Lipid rafts and human diseases: why we need to target gangliosides
by: Jacques Fantini
Published: (2023-09-01) -
Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins
by: Farhana Yesmin, et al.
Published: (2021-12-01) -
A Vaccine Strategy Based on the Identification of an Annular Ganglioside Binding Motif in Monkeypox Virus Protein E8L
by: Jacques Fantini, et al.
Published: (2022-11-01) -
The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program
by: Fodil Azzaz, et al.
Published: (2022-10-01)