Gene by Culture Effects on Emotional Processing of Social Cues among East Asians and European Americans
While Western cultures are more focused on individualization and self-expression, East Asian cultures promote interrelatedness. Largely unknown is how gene by culture interactions influence the degree to which individuals acquire culture, and the neurocircuitry underlying how social cues are process...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-07-01
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| Series: | Behavioral Sciences |
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| Online Access: | http://www.mdpi.com/2076-328X/8/7/62 |
| _version_ | 1819295003782938624 |
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| author | Arash Javanbakht Steve Tompson Shinobu Kitayama Anthony King Carolyn Yoon Israel Liberzon |
| author_facet | Arash Javanbakht Steve Tompson Shinobu Kitayama Anthony King Carolyn Yoon Israel Liberzon |
| author_sort | Arash Javanbakht |
| collection | DOAJ |
| description | While Western cultures are more focused on individualization and self-expression, East Asian cultures promote interrelatedness. Largely unknown is how gene by culture interactions influence the degree to which individuals acquire culture, and the neurocircuitry underlying how social cues are processed. We sought to examine the interaction between DRD4 polymorphism and culture in the neural processing of social emotional cues. 19 Asian-born East Asian (AA) and 20 European American (EA) participants performed a shifted attention emotion appraisal functional magnetic resonance imaging (fMRI) task, which probes implicit emotional processing and regulation in response to social emotional cues. Half of the participants in each group were DRD4 2- or 7-repeat allele (2R/7R) carriers. AA participants showed larger left and right amygdala, and left hippocampal activation during implicit processing of fearful faces. There was a gene by culture interaction in the left insula during implicit processing of facial cues, while activation in EA DRD4 2R/7R carriers was larger than EA non-carriers and AA carriers. Our findings suggest that emotional facial cues are more salient to AA participants and elicit a larger amygdala reaction. Gene by culture interaction finding in insula suggests that DRD4 2R/7R carriers in each culture are more prone to adopting their cultural norm. |
| first_indexed | 2024-12-24T04:35:19Z |
| format | Article |
| id | doaj.art-e4dbe4da475f4abebc3d27949a0ee2b7 |
| institution | Directory Open Access Journal |
| issn | 2076-328X |
| language | English |
| last_indexed | 2024-12-24T04:35:19Z |
| publishDate | 2018-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Behavioral Sciences |
| spelling | doaj.art-e4dbe4da475f4abebc3d27949a0ee2b72022-12-21T17:15:14ZengMDPI AGBehavioral Sciences2076-328X2018-07-01876210.3390/bs8070062bs8070062Gene by Culture Effects on Emotional Processing of Social Cues among East Asians and European AmericansArash Javanbakht0Steve Tompson1Shinobu Kitayama2Anthony King3Carolyn Yoon4Israel Liberzon5Department of Psychiatry and Behavioral Neurosciences, Wayne State University, 3901 Chrysler Service Drive, 3rd Floor, Detroit, MI 48201, USADepartment of Psychology, University of Michigan, 3217 East Hall, Ann Arbor, MI 48109, USADepartment of Psychology, University of Michigan, 3217 East Hall, Ann Arbor, MI 48109, USADepartment of Psychiatry, University of Michigan, 4250 Plymouth Rd., Ann Arbor, MI 48109, USAStephen M. Ross School of Business, University of Michigan, 701 Tappan Ave, Ann Arbor, MI 48109, USADepartment of Psychiatry, University of Michigan, 4250 Plymouth Rd., Ann Arbor, MI 48109, USAWhile Western cultures are more focused on individualization and self-expression, East Asian cultures promote interrelatedness. Largely unknown is how gene by culture interactions influence the degree to which individuals acquire culture, and the neurocircuitry underlying how social cues are processed. We sought to examine the interaction between DRD4 polymorphism and culture in the neural processing of social emotional cues. 19 Asian-born East Asian (AA) and 20 European American (EA) participants performed a shifted attention emotion appraisal functional magnetic resonance imaging (fMRI) task, which probes implicit emotional processing and regulation in response to social emotional cues. Half of the participants in each group were DRD4 2- or 7-repeat allele (2R/7R) carriers. AA participants showed larger left and right amygdala, and left hippocampal activation during implicit processing of fearful faces. There was a gene by culture interaction in the left insula during implicit processing of facial cues, while activation in EA DRD4 2R/7R carriers was larger than EA non-carriers and AA carriers. Our findings suggest that emotional facial cues are more salient to AA participants and elicit a larger amygdala reaction. Gene by culture interaction finding in insula suggests that DRD4 2R/7R carriers in each culture are more prone to adopting their cultural norm.http://www.mdpi.com/2076-328X/8/7/62culturegeneemotionsocialamygdalainsula |
| spellingShingle | Arash Javanbakht Steve Tompson Shinobu Kitayama Anthony King Carolyn Yoon Israel Liberzon Gene by Culture Effects on Emotional Processing of Social Cues among East Asians and European Americans Behavioral Sciences culture gene emotion social amygdala insula |
| title | Gene by Culture Effects on Emotional Processing of Social Cues among East Asians and European Americans |
| title_full | Gene by Culture Effects on Emotional Processing of Social Cues among East Asians and European Americans |
| title_fullStr | Gene by Culture Effects on Emotional Processing of Social Cues among East Asians and European Americans |
| title_full_unstemmed | Gene by Culture Effects on Emotional Processing of Social Cues among East Asians and European Americans |
| title_short | Gene by Culture Effects on Emotional Processing of Social Cues among East Asians and European Americans |
| title_sort | gene by culture effects on emotional processing of social cues among east asians and european americans |
| topic | culture gene emotion social amygdala insula |
| url | http://www.mdpi.com/2076-328X/8/7/62 |
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