UHPLC-MS/MS method for pharmacokinetic and bioavailability determination of five bioactive components in raw and various processed products of Polygala tenuifolia in rat plasma

UHPLC-MS/MS method for pharmacokinetic and bioavailability determination of five bioactive components in raw and various processed products of Polygala tenuifolia in rat plasma

Context Sibiricose A5 (A5), sibiricose A6 (A6), 3,6′-disinapoyl sucrose (DSS), tenuifoliside A (TFSA) and 3,4,5-trimethoxycinnamic acid (TMCA) are the main active components of Polygala tenuifolia Willd. (Polygalaceae) (PT) that are active against Alzheimer's disease. Objective To compare the p...

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Bibliographic Details
Main Authors:	Xin Zhao, Baoxin Xu, Peng Wu, Pan Zhao, Changchuan Guo, Yueli Cui, Yanxue Zhang, Xuelan Zhang, Huifen Li
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-01-01
Series:	Pharmaceutical Biology
Subjects:	liquorice boiling honey stir-baking sibiricose a5 sibiricose a6 3,6′-disinapoyl sucrose tenuifoliside a 3,4,5-trimethoxycinnamic acid
Online Access:	http://dx.doi.org/10.1080/13880209.2020.1818790

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