Divisively normalized neuronal processing of uncertain visual feedback for visuomotor learning
Abstract When encountering a visual error during a reaching movement, the motor system improves the motor command for the subsequent trial. This improvement is impaired by visual error uncertainty, which is considered evidence that the motor system optimally estimates the error. However, how such st...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-12-01
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| Series: | Communications Biology |
| Online Access: | https://doi.org/10.1038/s42003-023-05578-4 |
| _version_ | 1797376875594514432 |
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| author | Yuto Makino Takuji Hayashi Daichi Nozaki |
| author_facet | Yuto Makino Takuji Hayashi Daichi Nozaki |
| author_sort | Yuto Makino |
| collection | DOAJ |
| description | Abstract When encountering a visual error during a reaching movement, the motor system improves the motor command for the subsequent trial. This improvement is impaired by visual error uncertainty, which is considered evidence that the motor system optimally estimates the error. However, how such statistical computation is accomplished remains unclear. Here, we propose an alternative scheme implemented with a divisive normalization (DN): the responses of neuronal elements are normalized by the summed activity of the population. This scheme assumes that when an uncertain visual error is provided by multiple cursors, the motor system processes the error conveyed by each cursor and integrates the information using DN. The DN model reproduced the patterns of learning response to 1-3 cursor errors and the impairment of learning response with visual error uncertainty. This study provides a new perspective on how the motor system updates motor commands according to uncertain visual error information. |
| first_indexed | 2024-03-08T19:44:54Z |
| format | Article |
| id | doaj.art-e4ddf623360343348a5d8d529264c32c |
| institution | Directory Open Access Journal |
| issn | 2399-3642 |
| language | English |
| last_indexed | 2024-03-08T19:44:54Z |
| publishDate | 2023-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Communications Biology |
| spelling | doaj.art-e4ddf623360343348a5d8d529264c32c2023-12-24T12:26:35ZengNature PortfolioCommunications Biology2399-36422023-12-016111410.1038/s42003-023-05578-4Divisively normalized neuronal processing of uncertain visual feedback for visuomotor learningYuto Makino0Takuji Hayashi1Daichi Nozaki2Division of Physical and Health Education, Graduate School of Education, The University of TokyoDivision of Physical and Health Education, Graduate School of Education, The University of TokyoDivision of Physical and Health Education, Graduate School of Education, The University of TokyoAbstract When encountering a visual error during a reaching movement, the motor system improves the motor command for the subsequent trial. This improvement is impaired by visual error uncertainty, which is considered evidence that the motor system optimally estimates the error. However, how such statistical computation is accomplished remains unclear. Here, we propose an alternative scheme implemented with a divisive normalization (DN): the responses of neuronal elements are normalized by the summed activity of the population. This scheme assumes that when an uncertain visual error is provided by multiple cursors, the motor system processes the error conveyed by each cursor and integrates the information using DN. The DN model reproduced the patterns of learning response to 1-3 cursor errors and the impairment of learning response with visual error uncertainty. This study provides a new perspective on how the motor system updates motor commands according to uncertain visual error information.https://doi.org/10.1038/s42003-023-05578-4 |
| spellingShingle | Yuto Makino Takuji Hayashi Daichi Nozaki Divisively normalized neuronal processing of uncertain visual feedback for visuomotor learning Communications Biology |
| title | Divisively normalized neuronal processing of uncertain visual feedback for visuomotor learning |
| title_full | Divisively normalized neuronal processing of uncertain visual feedback for visuomotor learning |
| title_fullStr | Divisively normalized neuronal processing of uncertain visual feedback for visuomotor learning |
| title_full_unstemmed | Divisively normalized neuronal processing of uncertain visual feedback for visuomotor learning |
| title_short | Divisively normalized neuronal processing of uncertain visual feedback for visuomotor learning |
| title_sort | divisively normalized neuronal processing of uncertain visual feedback for visuomotor learning |
| url | https://doi.org/10.1038/s42003-023-05578-4 |
| work_keys_str_mv | AT yutomakino divisivelynormalizedneuronalprocessingofuncertainvisualfeedbackforvisuomotorlearning AT takujihayashi divisivelynormalizedneuronalprocessingofuncertainvisualfeedbackforvisuomotorlearning AT daichinozaki divisivelynormalizedneuronalprocessingofuncertainvisualfeedbackforvisuomotorlearning |