Dendrimers Target the Ischemic Lesion in Rodent and Primate Models of Nonarteritic Anterior Ischemic Optic Neuropathy.

Dendrimers Target the Ischemic Lesion in Rodent and Primate Models of Nonarteritic Anterior Ischemic Optic Neuropathy.

INTRODUCTION:Polyamidoamine dendrimer nanoparticles (~ 4 nanometers) are inert polymers that can be linked to biologically active compounds. These dendrimers selectively target and accumulate in inflammatory cells upon systemic administration. Dendrimer-linked compounds enable sustained release of t...

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Bibliografiska uppgifter
Huvudupphovsmän: Yan Guo, Mary A Johnson, Zara Mehrabian, Manoj K Mishra, Rangaramanujam Kannan, Neil R Miller, Steven L Bernstein
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2016-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC4851377?pdf=render

Internet

http://europepmc.org/articles/PMC4851377?pdf=render

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