Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis

Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis

<p>Abstract</p> <p>Background</p> <p>Single drug use has not achieved satisfactory results in the treatment of prostate cancer, despite application of increasingly widespread targeted therapeutics. In the present study, the combined impact of the mammalian target of rap...

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Bibliographic Details
Main Authors: Waaga-Gasser Ana, Tsaur Igor, Juengel Eva, Makarević Jasmina, Seibel Jens-Michael, Hudak Lukasz, Wedel Steffen, Haferkamp Axel, Blaheta Roman A
Format: Article
Language:English
Published: BMC 2011-08-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/11/375

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