Global trends in research on endothelial cells and sepsis between 2002 and 2022: A systematic bibliometric analysis
Sepsis is a systemic syndrome involving physiological, pathological, and biochemical abnormalities precipitated by infection and is a major global public health problem. Endothelial cells (ECs) dysfunction is a major contributor to sepsis-induced multiple organ failure. This bibliometric analysis ai...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023108073 |
| _version_ | 1797336996228628480 |
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| author | Yue Shi Shunpan Ji Yuhai Xu Jun Ji Xiaoming Yang Bo Ye Jingsheng Lou Tianzhu Tao |
| author_facet | Yue Shi Shunpan Ji Yuhai Xu Jun Ji Xiaoming Yang Bo Ye Jingsheng Lou Tianzhu Tao |
| author_sort | Yue Shi |
| collection | DOAJ |
| description | Sepsis is a systemic syndrome involving physiological, pathological, and biochemical abnormalities precipitated by infection and is a major global public health problem. Endothelial cells (ECs) dysfunction is a major contributor to sepsis-induced multiple organ failure. This bibliometric analysis aimed to identify and characterize the status, evolution of the field, and new research trends of ECs and sepsis over the past 20 years.For this analysis, the Web of Science Core Collection database was searched to identify relevant publications on ECs in sepsis published between January 1, 2002, and December 31, 2022. Microsoft Excel 2021, VOSviewer software, CiteSpace software, and the online analysis platform of literature metrology (http://bibliometric.com) were used to visualize the trends of publications’ countries/regions, institutions, authors, journals, and keywords.In total, 4200 articles were identified and screened, primarily originating from 86 countries/regions and 3489 institutions. The USA was the leading contributor to this research field, providing 1501 articles (35.74 %). Harvard University's scientists were the most prolific, with 129 articles. Overall, 21,944 authors were identified, among whom Bae Jong Sup was the most prolific, contributing 129 publications. Additionally, Levi Marcel was the most frequently co-cited author, appearing 538 times. The journals that published the most articles were SHOCK, CRITICAL CARE MEDICINE, and PLOS ONE, accounting for 10.79 % of the total. The current emerging hotspots are concentrated on ''endothelial glycocalyx,'' ''NLRP3 inflammasome,'' ''extracellular vesicle,'' ''biomarkers,'' and ''COVID-19,'' among others.In conclusion, this study provides a comprehensive overview of the scientific productivity and emerging research trends in the field of ECs in sepsis. The evidence supporting the significant role of ECs in both physiological and pathological responses to sepsis is continuously growing. More in-depth studies of the molecular mechanisms underlying sepsis-induced endothelial dysfunction and EC-targeted therapies are warranted in the future. |
| first_indexed | 2024-03-08T09:02:59Z |
| format | Article |
| id | doaj.art-e4e275e4f8674b4799689ddc990b51bb |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T09:02:59Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-e4e275e4f8674b4799689ddc990b51bb2024-02-01T06:32:35ZengElsevierHeliyon2405-84402024-01-01101e23599Global trends in research on endothelial cells and sepsis between 2002 and 2022: A systematic bibliometric analysisYue Shi0Shunpan Ji1Yuhai Xu2Jun Ji3Xiaoming Yang4Bo Ye5Jingsheng Lou6Tianzhu Tao7Department of Anesthesiology, Air Force Medical Center, Beijing, China; Graduate of China Medical University, Shenyang, ChinaDepartment of Anesthesiology, Air Force Medical Center, Beijing, China; Graduate of China Medical University, Shenyang, ChinaDepartment of Anesthesiology, Air Force Medical Center, Beijing, ChinaDepartment of Anesthesiology, Air Force Medical Center, Beijing, ChinaDepartment of Anesthesiology, Air Force Medical Center, Beijing, ChinaDepartment of Anesthesiology, Air Force Medical Center, Beijing, China; Graduate of China Medical University, Shenyang, ChinaDepartment of Anesthesiology, The General Hospital of the People's Liberation Army, Beijing, China; Corresponding author.Department of Anesthesiology, Air Force Medical Center, Beijing, China; Graduate of China Medical University, Shenyang, China; Corresponding author. Department of Anesthesiology, Air Force Medical Center, Beijing, China.Sepsis is a systemic syndrome involving physiological, pathological, and biochemical abnormalities precipitated by infection and is a major global public health problem. Endothelial cells (ECs) dysfunction is a major contributor to sepsis-induced multiple organ failure. This bibliometric analysis aimed to identify and characterize the status, evolution of the field, and new research trends of ECs and sepsis over the past 20 years.For this analysis, the Web of Science Core Collection database was searched to identify relevant publications on ECs in sepsis published between January 1, 2002, and December 31, 2022. Microsoft Excel 2021, VOSviewer software, CiteSpace software, and the online analysis platform of literature metrology (http://bibliometric.com) were used to visualize the trends of publications’ countries/regions, institutions, authors, journals, and keywords.In total, 4200 articles were identified and screened, primarily originating from 86 countries/regions and 3489 institutions. The USA was the leading contributor to this research field, providing 1501 articles (35.74 %). Harvard University's scientists were the most prolific, with 129 articles. Overall, 21,944 authors were identified, among whom Bae Jong Sup was the most prolific, contributing 129 publications. Additionally, Levi Marcel was the most frequently co-cited author, appearing 538 times. The journals that published the most articles were SHOCK, CRITICAL CARE MEDICINE, and PLOS ONE, accounting for 10.79 % of the total. The current emerging hotspots are concentrated on ''endothelial glycocalyx,'' ''NLRP3 inflammasome,'' ''extracellular vesicle,'' ''biomarkers,'' and ''COVID-19,'' among others.In conclusion, this study provides a comprehensive overview of the scientific productivity and emerging research trends in the field of ECs in sepsis. The evidence supporting the significant role of ECs in both physiological and pathological responses to sepsis is continuously growing. More in-depth studies of the molecular mechanisms underlying sepsis-induced endothelial dysfunction and EC-targeted therapies are warranted in the future.http://www.sciencedirect.com/science/article/pii/S2405844023108073Endothelial cellsEndotheliumSepsisBibliometricPermeabilityGlycocalyx |
| spellingShingle | Yue Shi Shunpan Ji Yuhai Xu Jun Ji Xiaoming Yang Bo Ye Jingsheng Lou Tianzhu Tao Global trends in research on endothelial cells and sepsis between 2002 and 2022: A systematic bibliometric analysis Heliyon Endothelial cells Endothelium Sepsis Bibliometric Permeability Glycocalyx |
| title | Global trends in research on endothelial cells and sepsis between 2002 and 2022: A systematic bibliometric analysis |
| title_full | Global trends in research on endothelial cells and sepsis between 2002 and 2022: A systematic bibliometric analysis |
| title_fullStr | Global trends in research on endothelial cells and sepsis between 2002 and 2022: A systematic bibliometric analysis |
| title_full_unstemmed | Global trends in research on endothelial cells and sepsis between 2002 and 2022: A systematic bibliometric analysis |
| title_short | Global trends in research on endothelial cells and sepsis between 2002 and 2022: A systematic bibliometric analysis |
| title_sort | global trends in research on endothelial cells and sepsis between 2002 and 2022 a systematic bibliometric analysis |
| topic | Endothelial cells Endothelium Sepsis Bibliometric Permeability Glycocalyx |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023108073 |
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