The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective study
Background: Helicobacter pylori (H. pylori) infection is highly prevalent globally and half of the world’s population are carrying the pathogen with infection rates higher in low and middle-income countries. The study aim was to retrospectively determine the seroprevalence trend of H. pylori infecti...
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| Format: | Article |
| Language: | English |
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Zagazig University, Faculty of Medicine
2022-10-01
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| Series: | Microbes and Infectious Diseases |
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| Online Access: | https://mid.journals.ekb.eg/article_223024_b547c6fcd797f5e1aed1462c166b26d4.pdf |
| _version_ | 1797989269243953152 |
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| author | Yakubu Ibrahim Lateef Famoriyo Fatima Sani Nurul Iftida Basri Amilia Afzan Mohd Muhammad Abdurrahman Idris Abdullahi |
| author_facet | Yakubu Ibrahim Lateef Famoriyo Fatima Sani Nurul Iftida Basri Amilia Afzan Mohd Muhammad Abdurrahman Idris Abdullahi |
| author_sort | Yakubu Ibrahim |
| collection | DOAJ |
| description | Background: Helicobacter pylori (H. pylori) infection is highly prevalent globally and half of the world’s population are carrying the pathogen with infection rates higher in low and middle-income countries. The study aim was to retrospectively determine the seroprevalence trend of H. pylori infection among patients suspected to have dyspepsia and identify socio-demographic determinants for H. pylori seropositivity. Methods: This retrospective study was conducted at the State Specialist Hospital, Gombe, Nigeria from January 2015 to December 2019. A total of 11,935 patients were included in the study and lateral flow immunochromatographic immuno assay was used to screen for total anti H. pylori antibodies. Results: The overall sero-prevalence of H. pylori infection was 58.9%. There was significant association between H. pylori seroprevalence rate and age of subjects, (χ2=20.86; p < /em><0.001). The study subjects between the age group 31-40 years had the highest seroprevalence, 62.3%. The seroprevalence of H. pylori was associated with sex of subjects (χ2=39.73; p < /em><0.0001). The seroprevalence trend of H. pylori was highest in 2016 with 61%, followed by 2019 (60.8%), then 2017 (59.3%), 2018 (54.7%) and least in 2015 (50.5%). Conclusion: Findings from the study showed a steady rise in the seroprevalence of H. pylori infection over the five years of study. Furthermore, H pylori infection appears to be higher among adults in their most productive years. Based on these, it is needful to develop strategies for eradication of the infection, encourage health education by creating awareness towards improving environmental and household sanitation, water, personal and food hygiene. |
| first_indexed | 2024-04-11T08:17:27Z |
| format | Article |
| id | doaj.art-e4e53a044a9a4111af919c04654214c1 |
| institution | Directory Open Access Journal |
| issn | 2682-4132 2682-4140 |
| language | English |
| last_indexed | 2024-04-11T08:17:27Z |
| publishDate | 2022-10-01 |
| publisher | Zagazig University, Faculty of Medicine |
| record_format | Article |
| series | Microbes and Infectious Diseases |
| spelling | doaj.art-e4e53a044a9a4111af919c04654214c12022-12-22T04:35:06ZengZagazig University, Faculty of MedicineMicrobes and Infectious Diseases2682-41322682-41402022-10-01341016102510.21608/mid.2022.120290.1245223024The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective studyYakubu Ibrahim0Lateef Famoriyo1Fatima Sani2Nurul Iftida Basri3Amilia Afzan Mohd4Muhammad Abdurrahman5Idris Abdullahi6Department of Medical Laboratory Sciences, College of Medical Sciences, Ahmadu Bello University, Zaria, Kaduna State, Nigeria.Medical Laboratory Services Department, Gombe State Specialist Hospital, Gombe, NigeriaDepartment of Microbiology, Faculty of Science, Gombe State University, Tudunwada, Gombe, NigeriaDepartment of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, MalaysiaDepartment of Obstetrics and Gynaecology. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400, Serdang, Selangor, MalaysiaDepartment of Medical Laboratory Science, Faculty of Allied Health Sciences, College of Health Sciences, Bayero University, Kano, Kano State, NigeriaDepartment of Medical Laboratory Science, Faculty of Allied Health Sciences, College of Medical Sciences, Ahmadu Bello University Zaria, NigeriaBackground: Helicobacter pylori (H. pylori) infection is highly prevalent globally and half of the world’s population are carrying the pathogen with infection rates higher in low and middle-income countries. The study aim was to retrospectively determine the seroprevalence trend of H. pylori infection among patients suspected to have dyspepsia and identify socio-demographic determinants for H. pylori seropositivity. Methods: This retrospective study was conducted at the State Specialist Hospital, Gombe, Nigeria from January 2015 to December 2019. A total of 11,935 patients were included in the study and lateral flow immunochromatographic immuno assay was used to screen for total anti H. pylori antibodies. Results: The overall sero-prevalence of H. pylori infection was 58.9%. There was significant association between H. pylori seroprevalence rate and age of subjects, (χ2=20.86; p < /em><0.001). The study subjects between the age group 31-40 years had the highest seroprevalence, 62.3%. The seroprevalence of H. pylori was associated with sex of subjects (χ2=39.73; p < /em><0.0001). The seroprevalence trend of H. pylori was highest in 2016 with 61%, followed by 2019 (60.8%), then 2017 (59.3%), 2018 (54.7%) and least in 2015 (50.5%). Conclusion: Findings from the study showed a steady rise in the seroprevalence of H. pylori infection over the five years of study. Furthermore, H pylori infection appears to be higher among adults in their most productive years. Based on these, it is needful to develop strategies for eradication of the infection, encourage health education by creating awareness towards improving environmental and household sanitation, water, personal and food hygiene.https://mid.journals.ekb.eg/article_223024_b547c6fcd797f5e1aed1462c166b26d4.pdfhelicobacter pyloriprevalencenigeriahygieneretrospective studies |
| spellingShingle | Yakubu Ibrahim Lateef Famoriyo Fatima Sani Nurul Iftida Basri Amilia Afzan Mohd Muhammad Abdurrahman Idris Abdullahi The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective study Microbes and Infectious Diseases helicobacter pylori prevalence nigeria hygiene retrospective studies |
| title | The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective study |
| title_full | The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective study |
| title_fullStr | The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective study |
| title_full_unstemmed | The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective study |
| title_short | The seroprevalence trend of Helicobacter pylori infection in Gombe, Nigeria: A 5-year retrospective study |
| title_sort | seroprevalence trend of helicobacter pylori infection in gombe nigeria a 5 year retrospective study |
| topic | helicobacter pylori prevalence nigeria hygiene retrospective studies |
| url | https://mid.journals.ekb.eg/article_223024_b547c6fcd797f5e1aed1462c166b26d4.pdf |
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