Psychotic symptoms due to topiramate
Topiramate is an antiepileptic drug prescribed in the treatment of numerous psychiatric disorders and in epilepsy. Topiramate exerts its antiepileptic effect through different mechanisms, such as by the blockage of sodium channels, increasing GABAergic neurotransmission, antagonizing excitatory am...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Medical Communications Sp. z o.o.
2015-04-01
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| Series: | Psychiatria i Psychologia Kliniczna |
| Subjects: | |
| Online Access: | http://www.psychiatria.com.pl/index.php/wydawnictwa/2015-vol-15-no-1/psychotic-symptoms-due-to-topiramate?aid=508 |
| _version_ | 1811284269904953344 |
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| author | Gülay Oğuz Mükerrem Güven Saime Çağlı Sedat Batmaz |
| author_facet | Gülay Oğuz Mükerrem Güven Saime Çağlı Sedat Batmaz |
| author_sort | Gülay Oğuz |
| collection | DOAJ |
| description | Topiramate is an antiepileptic drug prescribed in the treatment of numerous psychiatric disorders and in epilepsy.
Topiramate exerts its antiepileptic effect through different mechanisms, such as by the blockage of sodium channels,
increasing GABAergic neurotransmission, antagonizing excitatory amino acid receptors (glutamate) or blocking
calcium channels. Its prescription in psychiatric diseases has increased in recent years and psychotic symptom
development due to the usage of topiramate has been observed in some studies. Therefore, it is essential to evaluate
the patient for psychotic symptoms while using topiramate. This article presents a case of a 37-year-old woman
who developed depression, anxiety and auditory hallucinations during the treatment with 150 mg of topiramate.
After stopping topiramate, 5 mg of olanzapine bid was started and the symptoms gradually decreased and finally
disappeared. |
| first_indexed | 2024-04-13T02:25:56Z |
| format | Article |
| id | doaj.art-e4e72b83cdeb460fa32103cd764a2dce |
| institution | Directory Open Access Journal |
| issn | 1644-6313 2451-0645 |
| language | English |
| last_indexed | 2024-04-13T02:25:56Z |
| publishDate | 2015-04-01 |
| publisher | Medical Communications Sp. z o.o. |
| record_format | Article |
| series | Psychiatria i Psychologia Kliniczna |
| spelling | doaj.art-e4e72b83cdeb460fa32103cd764a2dce2022-12-22T03:06:47ZengMedical Communications Sp. z o.o.Psychiatria i Psychologia Kliniczna1644-63132451-06452015-04-01151384010.15557/PiPK.2015.0006Psychotic symptoms due to topiramateGülay Oğuz0Mükerrem Güven1Saime Çağlı2Sedat Batmaz3Department of Psychology, Faculty of Science and Letters, Canik Başarı University, Samsun, TurkeyDepartment of Psychiatry, Akdeniz University, School of Medicine, Antalya, TurkeyPrivate Practice, Samsun, TurkeyDepartment of Psychiatry, Gaziosmanpaşa University, School of Medicine, Tokat, TurkeyTopiramate is an antiepileptic drug prescribed in the treatment of numerous psychiatric disorders and in epilepsy. Topiramate exerts its antiepileptic effect through different mechanisms, such as by the blockage of sodium channels, increasing GABAergic neurotransmission, antagonizing excitatory amino acid receptors (glutamate) or blocking calcium channels. Its prescription in psychiatric diseases has increased in recent years and psychotic symptom development due to the usage of topiramate has been observed in some studies. Therefore, it is essential to evaluate the patient for psychotic symptoms while using topiramate. This article presents a case of a 37-year-old woman who developed depression, anxiety and auditory hallucinations during the treatment with 150 mg of topiramate. After stopping topiramate, 5 mg of olanzapine bid was started and the symptoms gradually decreased and finally disappeared.http://www.psychiatria.com.pl/index.php/wydawnictwa/2015-vol-15-no-1/psychotic-symptoms-due-to-topiramate?aid=508auditory hallucinationspsychotic symptomstopiramate |
| spellingShingle | Gülay Oğuz Mükerrem Güven Saime Çağlı Sedat Batmaz Psychotic symptoms due to topiramate Psychiatria i Psychologia Kliniczna auditory hallucinations psychotic symptoms topiramate |
| title | Psychotic symptoms due to topiramate |
| title_full | Psychotic symptoms due to topiramate |
| title_fullStr | Psychotic symptoms due to topiramate |
| title_full_unstemmed | Psychotic symptoms due to topiramate |
| title_short | Psychotic symptoms due to topiramate |
| title_sort | psychotic symptoms due to topiramate |
| topic | auditory hallucinations psychotic symptoms topiramate |
| url | http://www.psychiatria.com.pl/index.php/wydawnictwa/2015-vol-15-no-1/psychotic-symptoms-due-to-topiramate?aid=508 |
| work_keys_str_mv | AT gulayoguz psychoticsymptomsduetotopiramate AT mukerremguven psychoticsymptomsduetotopiramate AT saimecaglı psychoticsymptomsduetotopiramate AT sedatbatmaz psychoticsymptomsduetotopiramate |